Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress

The nucleolus is a specialized functional domain of the nucleus where ribosome biogenesis is initiated and also implicated in a p53-dependent anti-tumor surveillance. Here the authors use a quantitative imaging approach to detail the role of each ribosomal protein on the structural integrity of the...

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Autores principales:	Emilien Nicolas, Pascaline Parisot, Celina Pinto-Monteiro, Roxane de Walque, Christophe De Vleeschouwer, Denis L. J. Lafontaine
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a3e1be32abf34328a408ce075cdfbd0f
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spelling	oai:doaj.org-article:a3e1be32abf34328a408ce075cdfbd0f2021-12-02T14:39:13ZInvolvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress10.1038/ncomms113902041-1723https://doaj.org/article/a3e1be32abf34328a408ce075cdfbd0f2016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11390https://doaj.org/toc/2041-1723The nucleolus is a specialized functional domain of the nucleus where ribosome biogenesis is initiated and also implicated in a p53-dependent anti-tumor surveillance. Here the authors use a quantitative imaging approach to detail the role of each ribosomal protein on the structural integrity of the nucleolus and p53 homeostasis.Emilien NicolasPascaline ParisotCelina Pinto-MonteiroRoxane de WalqueChristophe De VleeschouwerDenis L. J. LafontaineNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Emilien Nicolas Pascaline Parisot Celina Pinto-Monteiro Roxane de Walque Christophe De Vleeschouwer Denis L. J. Lafontaine Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress
description	The nucleolus is a specialized functional domain of the nucleus where ribosome biogenesis is initiated and also implicated in a p53-dependent anti-tumor surveillance. Here the authors use a quantitative imaging approach to detail the role of each ribosomal protein on the structural integrity of the nucleolus and p53 homeostasis.
format	article
author	Emilien Nicolas Pascaline Parisot Celina Pinto-Monteiro Roxane de Walque Christophe De Vleeschouwer Denis L. J. Lafontaine
author_facet	Emilien Nicolas Pascaline Parisot Celina Pinto-Monteiro Roxane de Walque Christophe De Vleeschouwer Denis L. J. Lafontaine
author_sort	Emilien Nicolas
title	Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress
title_short	Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress
title_full	Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress
title_fullStr	Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress
title_full_unstemmed	Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress
title_sort	involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/a3e1be32abf34328a408ce075cdfbd0f
work_keys_str_mv	AT emiliennicolas involvementofhumanribosomalproteinsinnucleolarstructureandp53dependentnucleolarstress AT pascalineparisot involvementofhumanribosomalproteinsinnucleolarstructureandp53dependentnucleolarstress AT celinapintomonteiro involvementofhumanribosomalproteinsinnucleolarstructureandp53dependentnucleolarstress AT roxanedewalque involvementofhumanribosomalproteinsinnucleolarstructureandp53dependentnucleolarstress AT christophedevleeschouwer involvementofhumanribosomalproteinsinnucleolarstructureandp53dependentnucleolarstress AT denisljlafontaine involvementofhumanribosomalproteinsinnucleolarstructureandp53dependentnucleolarstress
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Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress

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