The transcription factor Foxp1 preserves integrity of an active Foxp3 locus in extrathymic Treg cells
Regulatory T (Treg) cells suppress immune cell activation to maintain immune homeostasis, and have their lineage enforced by the master transcription factor Foxp3. Here the authors show that Foxp3 expression is promoted and maintained by a related family member, Foxp1, specifically in peripherally i...
Enregistré dans:
Auteurs principaux: | Sayantani Ghosh, Sinchita Roy-Chowdhuri, Keunsoo Kang, Sin-Hyeog Im, Dipayan Rudra |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/a3e2bf22673043e1a4c02f20f2da2a40 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Foxp3+ Tregs are recruited to the retina to repair pathological angiogenesis
par: Devy Deliyanti, et autres
Publié: (2017) -
Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells
par: Stephanie Downs-Canner, et autres
Publié: (2017) -
Transcriptional regulation of FOXP3 requires integrated activation of both promoter and CNS regions in tumor-induced CD8+ Treg cells
par: Sreeparna Chakraborty, et autres
Publié: (2017) -
Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function
par: Jianbing Huang, et autres
Publié: (2017) -
Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases
par: Yuxiu Xu, et autres
Publié: (2021)