Development of a structural epitope mimic: an idiotypic approach to HCV vaccine design

Development of a structural epitope mimic: an idiotypic approach to HCV vaccine design

Abstract HCV vaccine development is stymied by the high genetic diversity of the virus and the variability of the envelope glycoproteins. One strategy to overcome this is to identify conserved, functionally important regions—such as the epitopes of broadly neutralizing antibodies (bNAbs)—and use the...

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Bibliographic Details
Main Authors: Vanessa M. Cowton, Ania M. Owsianka, Valeria Fadda, Ana Maria Ortega-Prieto, Sarah J. Cole, Jane A. Potter, Jessica K. Skelton, Nathan Jeffrey, Caterina Di Lorenzo, Marcus Dorner, Garry L. Taylor, Arvind H. Patel
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Immunologic diseases. Allergy
RC581-607
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Online Access:https://doaj.org/article/a3e8c908a1e3414390d0657b55f1aeda
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https://doaj.org/article/a3e8c908a1e3414390d0657b55f1aeda

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