Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression

Di Domenico et al., provide a comprehensive assessment of DNA methylation in a large cohort of pancreatic neuroendocrine tumors. This work provides new insights into the epigenetic heterogeneity of the disease and cellular basis.

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Autores principales:	Annunziata Di Domenico, Christodoulos P. Pipinikas, Renaud S. Maire, Konstantin Bräutigam, Cedric Simillion, Matthias S. Dettmer, Erik Vassella, Chrissie Thirlwell, Aurel Perren, Ilaria Marinoni
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/a3f12048273d452cbac17af8d0e13581
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spelling	oai:doaj.org-article:a3f12048273d452cbac17af8d0e135812021-12-02T15:18:51ZEpigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression10.1038/s42003-020-01479-y2399-3642https://doaj.org/article/a3f12048273d452cbac17af8d0e135812020-12-01T00:00:00Zhttps://doi.org/10.1038/s42003-020-01479-yhttps://doaj.org/toc/2399-3642Di Domenico et al., provide a comprehensive assessment of DNA methylation in a large cohort of pancreatic neuroendocrine tumors. This work provides new insights into the epigenetic heterogeneity of the disease and cellular basis.Annunziata Di DomenicoChristodoulos P. PipinikasRenaud S. MaireKonstantin BräutigamCedric SimillionMatthias S. DettmerErik VassellaChrissie ThirlwellAurel PerrenIlaria MarinoniNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Annunziata Di Domenico Christodoulos P. Pipinikas Renaud S. Maire Konstantin Bräutigam Cedric Simillion Matthias S. Dettmer Erik Vassella Chrissie Thirlwell Aurel Perren Ilaria Marinoni Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression
description	Di Domenico et al., provide a comprehensive assessment of DNA methylation in a large cohort of pancreatic neuroendocrine tumors. This work provides new insights into the epigenetic heterogeneity of the disease and cellular basis.
format	article
author	Annunziata Di Domenico Christodoulos P. Pipinikas Renaud S. Maire Konstantin Bräutigam Cedric Simillion Matthias S. Dettmer Erik Vassella Chrissie Thirlwell Aurel Perren Ilaria Marinoni
author_facet	Annunziata Di Domenico Christodoulos P. Pipinikas Renaud S. Maire Konstantin Bräutigam Cedric Simillion Matthias S. Dettmer Erik Vassella Chrissie Thirlwell Aurel Perren Ilaria Marinoni
author_sort	Annunziata Di Domenico
title	Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression
title_short	Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression
title_full	Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression
title_fullStr	Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression
title_full_unstemmed	Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression
title_sort	epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a3f12048273d452cbac17af8d0e13581
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Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression

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