Laugier-Hunziker syndrome: a case of asymptomatic mucosal and acral hyperpigmentation

Laugier-Hunziker syndrome (LHS) is a rare condition characterized by acquired hyperpigmentation involving the lips, oral mucosa, acral surfaces, nails and perineum. While patients with LHS may manifest pigmentation in all of the aforementioned areas, most present with pigmentation localized to only...

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Autores principales:	Elizabeth H. Cusick, Ashfaq A. Marghoob, Ralph P. Braun
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2017
Materias:	Laugier-Hunziker mucosal and acral hyperpigmentation mucocutaneous hyperpigmentation Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/a3f3b3e549884c1cac641c6952ab28af
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spelling	oai:doaj.org-article:a3f3b3e549884c1cac641c6952ab28af2021-11-17T08:30:44ZLaugier-Hunziker syndrome: a case of asymptomatic mucosal and acral hyperpigmentation10.5826/dpc.0702a052160-9381https://doaj.org/article/a3f3b3e549884c1cac641c6952ab28af2017-05-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/264https://doaj.org/toc/2160-9381 Laugier-Hunziker syndrome (LHS) is a rare condition characterized by acquired hyperpigmentation involving the lips, oral mucosa, acral surfaces, nails and perineum. While patients with LHS may manifest pigmentation in all of the aforementioned areas, most present with pigmentation localized to only a few of these anatomical sites. We herein report a patient exhibiting the characteristic pigment distribution pattern associated with LHS. Since LHS is a diagnosis based on exclusion, we discuss the differential diagnosis of mucocutaneous hyperpigmentation. Due to the benign nature of the disease, it is critical to differentiate this disorder from conditions with similar mucocutaneous pigmentary changes with somatic abnormalities that require medical management. We also explore potential mechanisms that may explain the pathogenesis of LHS. Elizabeth H. CusickAshfaq A. MarghoobRalph P. BraunMattioli1885articleLaugier-Hunzikermucosal and acral hyperpigmentationmucocutaneous hyperpigmentationDermatologyRL1-803ENDermatology Practical & Conceptual, Vol 7, Iss 2 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Laugier-Hunziker mucosal and acral hyperpigmentation mucocutaneous hyperpigmentation Dermatology RL1-803
spellingShingle	Laugier-Hunziker mucosal and acral hyperpigmentation mucocutaneous hyperpigmentation Dermatology RL1-803 Elizabeth H. Cusick Ashfaq A. Marghoob Ralph P. Braun Laugier-Hunziker syndrome: a case of asymptomatic mucosal and acral hyperpigmentation
description	Laugier-Hunziker syndrome (LHS) is a rare condition characterized by acquired hyperpigmentation involving the lips, oral mucosa, acral surfaces, nails and perineum. While patients with LHS may manifest pigmentation in all of the aforementioned areas, most present with pigmentation localized to only a few of these anatomical sites. We herein report a patient exhibiting the characteristic pigment distribution pattern associated with LHS. Since LHS is a diagnosis based on exclusion, we discuss the differential diagnosis of mucocutaneous hyperpigmentation. Due to the benign nature of the disease, it is critical to differentiate this disorder from conditions with similar mucocutaneous pigmentary changes with somatic abnormalities that require medical management. We also explore potential mechanisms that may explain the pathogenesis of LHS.
format	article
author	Elizabeth H. Cusick Ashfaq A. Marghoob Ralph P. Braun
author_facet	Elizabeth H. Cusick Ashfaq A. Marghoob Ralph P. Braun
author_sort	Elizabeth H. Cusick
title	Laugier-Hunziker syndrome: a case of asymptomatic mucosal and acral hyperpigmentation
title_short	Laugier-Hunziker syndrome: a case of asymptomatic mucosal and acral hyperpigmentation
title_full	Laugier-Hunziker syndrome: a case of asymptomatic mucosal and acral hyperpigmentation
title_fullStr	Laugier-Hunziker syndrome: a case of asymptomatic mucosal and acral hyperpigmentation
title_full_unstemmed	Laugier-Hunziker syndrome: a case of asymptomatic mucosal and acral hyperpigmentation
title_sort	laugier-hunziker syndrome: a case of asymptomatic mucosal and acral hyperpigmentation
publisher	Mattioli1885
publishDate	2017
url	https://doaj.org/article/a3f3b3e549884c1cac641c6952ab28af
work_keys_str_mv	AT elizabethhcusick laugierhunzikersyndromeacaseofasymptomaticmucosalandacralhyperpigmentation AT ashfaqamarghoob laugierhunzikersyndromeacaseofasymptomaticmucosalandacralhyperpigmentation AT ralphpbraun laugierhunzikersyndromeacaseofasymptomaticmucosalandacralhyperpigmentation
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Laugier-Hunziker syndrome: a case of asymptomatic mucosal and acral hyperpigmentation

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