Single-molecule detection with a millimetre-sized transistor

The sensing capability of nanometric transducers designed for label-free single molecule detection has been limited by the small number of recognition elements. Here, the authors demonstrate a millimetre-sized field effect transistor capable of selective single-molecule Immunoglobulin-G detection.

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Autores principales: Eleonora Macchia, Kyriaki Manoli, Brigitte Holzer, Cinzia Di Franco, Matteo Ghittorelli, Fabrizio Torricelli, Domenico Alberga, Giuseppe Felice Mangiatordi, Gerardo Palazzo, Gaetano Scamarcio, Luisa Torsi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/a3fb1f59bcb4472eae23de4a5bfa8193
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spelling oai:doaj.org-article:a3fb1f59bcb4472eae23de4a5bfa81932021-12-02T17:33:19ZSingle-molecule detection with a millimetre-sized transistor10.1038/s41467-018-05235-z2041-1723https://doaj.org/article/a3fb1f59bcb4472eae23de4a5bfa81932018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05235-zhttps://doaj.org/toc/2041-1723The sensing capability of nanometric transducers designed for label-free single molecule detection has been limited by the small number of recognition elements. Here, the authors demonstrate a millimetre-sized field effect transistor capable of selective single-molecule Immunoglobulin-G detection.Eleonora MacchiaKyriaki ManoliBrigitte HolzerCinzia Di FrancoMatteo GhittorelliFabrizio TorricelliDomenico AlbergaGiuseppe Felice MangiatordiGerardo PalazzoGaetano ScamarcioLuisa TorsiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Eleonora Macchia
Kyriaki Manoli
Brigitte Holzer
Cinzia Di Franco
Matteo Ghittorelli
Fabrizio Torricelli
Domenico Alberga
Giuseppe Felice Mangiatordi
Gerardo Palazzo
Gaetano Scamarcio
Luisa Torsi
Single-molecule detection with a millimetre-sized transistor
description The sensing capability of nanometric transducers designed for label-free single molecule detection has been limited by the small number of recognition elements. Here, the authors demonstrate a millimetre-sized field effect transistor capable of selective single-molecule Immunoglobulin-G detection.
format article
author Eleonora Macchia
Kyriaki Manoli
Brigitte Holzer
Cinzia Di Franco
Matteo Ghittorelli
Fabrizio Torricelli
Domenico Alberga
Giuseppe Felice Mangiatordi
Gerardo Palazzo
Gaetano Scamarcio
Luisa Torsi
author_facet Eleonora Macchia
Kyriaki Manoli
Brigitte Holzer
Cinzia Di Franco
Matteo Ghittorelli
Fabrizio Torricelli
Domenico Alberga
Giuseppe Felice Mangiatordi
Gerardo Palazzo
Gaetano Scamarcio
Luisa Torsi
author_sort Eleonora Macchia
title Single-molecule detection with a millimetre-sized transistor
title_short Single-molecule detection with a millimetre-sized transistor
title_full Single-molecule detection with a millimetre-sized transistor
title_fullStr Single-molecule detection with a millimetre-sized transistor
title_full_unstemmed Single-molecule detection with a millimetre-sized transistor
title_sort single-molecule detection with a millimetre-sized transistor
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/a3fb1f59bcb4472eae23de4a5bfa8193
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