Nascent RNA sequencing identifies a widespread sigma70-dependent pausing regulated by Gre factors in bacteria

Transcription by bacterial RNA polymerase is interrupted by pausing events that play diverse regulatory roles. Here, the authors find that a large number of E. coli sigma70-dependent pauses, clustered at a 10−20-bp distance from promoters, are regulated by Gre cleavage factors constituting a mechani...

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Bibliographic Details
Main Authors: Zhe Sun, Alexander V. Yakhnin, Peter C. FitzGerald, Carl E. Mclntosh, Mikhail Kashlev
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/a3fc4f3397f444a2a4e04ebfd6d6f34c
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