Phosphorylation of PUF-A/PUM3 on Y259 modulates PUF-A stability and cell proliferation.
Human PUF-A/PUM3 is a RNA and DNA binding protein participating in the nucleolar processing of 7S to 5.8S rRNA. The nucleolar localization of PUF-A redistributes to the nucleoplasm upon the exposure to genotoxic agents in cells. However, little is known regarding the roles of PUF-A in tumor progress...
Guardado en:
Autores principales: | Hung-Wei Lin, Jin-Yu Lee, Nai-Lin Chou, Ting-Wei Shih, Mau-Sun Chang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/a400f67bda40476188a07de2769a2575 |
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