Nasopharyngeal Carcinoma: Clinical Achievements and Considerations Among Treatment Options

Nasopharyngeal carcinoma (NPC) is a severe malignancy arising from the nasopharyngeal epithelium and is southern China’s third most common cancer. With the advancement of treatment methods, early-stage NPC patients usually have a better prognosis and more prolonged survival period than those with ot...

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Autores principales:	Zheran Liu, Ye Chen, Yonglin Su, Xiaolin Hu, Xingchen Peng
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	nasopharyngeal carcinoma intensity-modulated radiotherapy chemotherapy targeted therapy immunotherapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/a40675281eb54a84a44c230d2d55c73f
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spelling	oai:doaj.org-article:a40675281eb54a84a44c230d2d55c73f2021-12-01T13:43:42ZNasopharyngeal Carcinoma: Clinical Achievements and Considerations Among Treatment Options2234-943X10.3389/fonc.2021.635737https://doaj.org/article/a40675281eb54a84a44c230d2d55c73f2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fonc.2021.635737/fullhttps://doaj.org/toc/2234-943XNasopharyngeal carcinoma (NPC) is a severe malignancy arising from the nasopharyngeal epithelium and is southern China’s third most common cancer. With the advancement of treatment methods, early-stage NPC patients usually have a better prognosis and more prolonged survival period than those with other malignant tumors. Most treatment failures are due to distant metastasis or a locally advanced stage of NPC in the initial diagnosis. In addition, approximately 10% of patients develop local recurrence, and 10%–20% of patients experience distant metastasis after treatment. These patients have a poor prognosis, with a median survival of only approximately 10–15 months. In the rapid development of treatment options, the efficacy and safety of some treatments have been validated and approved for first-line treatment, while those of other treatments remain unclear. The present study aims to provide a comprehensive overview of recent advances in NPC treatment and explain the various therapeutic possibilities in treating locally advanced, recurrent, and metastatic NPC patients.Zheran LiuYe ChenYonglin SuYonglin SuXiaolin HuXingchen PengFrontiers Media S.A.articlenasopharyngeal carcinomaintensity-modulated radiotherapychemotherapytargeted therapyimmunotherapyNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENFrontiers in Oncology, Vol 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	nasopharyngeal carcinoma intensity-modulated radiotherapy chemotherapy targeted therapy immunotherapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	nasopharyngeal carcinoma intensity-modulated radiotherapy chemotherapy targeted therapy immunotherapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Zheran Liu Ye Chen Yonglin Su Yonglin Su Xiaolin Hu Xingchen Peng Nasopharyngeal Carcinoma: Clinical Achievements and Considerations Among Treatment Options
description	Nasopharyngeal carcinoma (NPC) is a severe malignancy arising from the nasopharyngeal epithelium and is southern China’s third most common cancer. With the advancement of treatment methods, early-stage NPC patients usually have a better prognosis and more prolonged survival period than those with other malignant tumors. Most treatment failures are due to distant metastasis or a locally advanced stage of NPC in the initial diagnosis. In addition, approximately 10% of patients develop local recurrence, and 10%–20% of patients experience distant metastasis after treatment. These patients have a poor prognosis, with a median survival of only approximately 10–15 months. In the rapid development of treatment options, the efficacy and safety of some treatments have been validated and approved for first-line treatment, while those of other treatments remain unclear. The present study aims to provide a comprehensive overview of recent advances in NPC treatment and explain the various therapeutic possibilities in treating locally advanced, recurrent, and metastatic NPC patients.
format	article
author	Zheran Liu Ye Chen Yonglin Su Yonglin Su Xiaolin Hu Xingchen Peng
author_facet	Zheran Liu Ye Chen Yonglin Su Yonglin Su Xiaolin Hu Xingchen Peng
author_sort	Zheran Liu
title	Nasopharyngeal Carcinoma: Clinical Achievements and Considerations Among Treatment Options
title_short	Nasopharyngeal Carcinoma: Clinical Achievements and Considerations Among Treatment Options
title_full	Nasopharyngeal Carcinoma: Clinical Achievements and Considerations Among Treatment Options
title_fullStr	Nasopharyngeal Carcinoma: Clinical Achievements and Considerations Among Treatment Options
title_full_unstemmed	Nasopharyngeal Carcinoma: Clinical Achievements and Considerations Among Treatment Options
title_sort	nasopharyngeal carcinoma: clinical achievements and considerations among treatment options
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/a40675281eb54a84a44c230d2d55c73f
work_keys_str_mv	AT zheranliu nasopharyngealcarcinomaclinicalachievementsandconsiderationsamongtreatmentoptions AT yechen nasopharyngealcarcinomaclinicalachievementsandconsiderationsamongtreatmentoptions AT yonglinsu nasopharyngealcarcinomaclinicalachievementsandconsiderationsamongtreatmentoptions AT yonglinsu nasopharyngealcarcinomaclinicalachievementsandconsiderationsamongtreatmentoptions AT xiaolinhu nasopharyngealcarcinomaclinicalachievementsandconsiderationsamongtreatmentoptions AT xingchenpeng nasopharyngealcarcinomaclinicalachievementsandconsiderationsamongtreatmentoptions
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Nasopharyngeal Carcinoma: Clinical Achievements and Considerations Among Treatment Options

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