Removal of back-reflection noise at ultrathin imaging probes by the single-core illumination and wide-field detection

Abstract Thin waveguides such as graded-index lenses and fiber bundles are often used as imaging probes for high-resolution endomicroscopes. However, strong back-reflection from the end surfaces of the probes makes it difficult for them to resolve weak contrast objects, especially in the reflectance...

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Autores principales:	Changhyeong Yoon, Munkyu Kang, Jin H. Hong, Taeseok D. Yang, Jingchao Xing, Hongki Yoo, Youngwoon Choi, Wonshik Choi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a409a91b80e74e01870f26cdfb37b5b9
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spelling	oai:doaj.org-article:a409a91b80e74e01870f26cdfb37b5b92021-12-02T11:53:05ZRemoval of back-reflection noise at ultrathin imaging probes by the single-core illumination and wide-field detection10.1038/s41598-017-07024-y2045-2322https://doaj.org/article/a409a91b80e74e01870f26cdfb37b5b92017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07024-yhttps://doaj.org/toc/2045-2322Abstract Thin waveguides such as graded-index lenses and fiber bundles are often used as imaging probes for high-resolution endomicroscopes. However, strong back-reflection from the end surfaces of the probes makes it difficult for them to resolve weak contrast objects, especially in the reflectance-mode imaging. Here we propose a method to spatially isolate illumination pathways from detection channels, and demonstrate wide-field reflectance imaging free from back-reflection noise. In the image fiber bundle, we send illumination light through individual core fibers and detect signals from target objects through the other fibers. The transmission matrix of the fiber bundle is measured and used to reconstruct a pixelation-free image. We demonstrated that the proposed imaging method improved 3.2 times on the signal to noise ratio produced by the conventional illumination-detection scheme.Changhyeong YoonMunkyu KangJin H. HongTaeseok D. YangJingchao XingHongki YooYoungwoon ChoiWonshik ChoiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Changhyeong Yoon Munkyu Kang Jin H. Hong Taeseok D. Yang Jingchao Xing Hongki Yoo Youngwoon Choi Wonshik Choi Removal of back-reflection noise at ultrathin imaging probes by the single-core illumination and wide-field detection
description	Abstract Thin waveguides such as graded-index lenses and fiber bundles are often used as imaging probes for high-resolution endomicroscopes. However, strong back-reflection from the end surfaces of the probes makes it difficult for them to resolve weak contrast objects, especially in the reflectance-mode imaging. Here we propose a method to spatially isolate illumination pathways from detection channels, and demonstrate wide-field reflectance imaging free from back-reflection noise. In the image fiber bundle, we send illumination light through individual core fibers and detect signals from target objects through the other fibers. The transmission matrix of the fiber bundle is measured and used to reconstruct a pixelation-free image. We demonstrated that the proposed imaging method improved 3.2 times on the signal to noise ratio produced by the conventional illumination-detection scheme.
format	article
author	Changhyeong Yoon Munkyu Kang Jin H. Hong Taeseok D. Yang Jingchao Xing Hongki Yoo Youngwoon Choi Wonshik Choi
author_facet	Changhyeong Yoon Munkyu Kang Jin H. Hong Taeseok D. Yang Jingchao Xing Hongki Yoo Youngwoon Choi Wonshik Choi
author_sort	Changhyeong Yoon
title	Removal of back-reflection noise at ultrathin imaging probes by the single-core illumination and wide-field detection
title_short	Removal of back-reflection noise at ultrathin imaging probes by the single-core illumination and wide-field detection
title_full	Removal of back-reflection noise at ultrathin imaging probes by the single-core illumination and wide-field detection
title_fullStr	Removal of back-reflection noise at ultrathin imaging probes by the single-core illumination and wide-field detection
title_full_unstemmed	Removal of back-reflection noise at ultrathin imaging probes by the single-core illumination and wide-field detection
title_sort	removal of back-reflection noise at ultrathin imaging probes by the single-core illumination and wide-field detection
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/a409a91b80e74e01870f26cdfb37b5b9
work_keys_str_mv	AT changhyeongyoon removalofbackreflectionnoiseatultrathinimagingprobesbythesinglecoreilluminationandwidefielddetection AT munkyukang removalofbackreflectionnoiseatultrathinimagingprobesbythesinglecoreilluminationandwidefielddetection AT jinhhong removalofbackreflectionnoiseatultrathinimagingprobesbythesinglecoreilluminationandwidefielddetection AT taeseokdyang removalofbackreflectionnoiseatultrathinimagingprobesbythesinglecoreilluminationandwidefielddetection AT jingchaoxing removalofbackreflectionnoiseatultrathinimagingprobesbythesinglecoreilluminationandwidefielddetection AT hongkiyoo removalofbackreflectionnoiseatultrathinimagingprobesbythesinglecoreilluminationandwidefielddetection AT youngwoonchoi removalofbackreflectionnoiseatultrathinimagingprobesbythesinglecoreilluminationandwidefielddetection AT wonshikchoi removalofbackreflectionnoiseatultrathinimagingprobesbythesinglecoreilluminationandwidefielddetection
_version_	1718394884227858432

Removal of back-reflection noise at ultrathin imaging probes by the single-core illumination and wide-field detection

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