Immune thrombocytopenia relapse post covid-19 vaccine in young male patient

Immune thrombocytopenic purpura (ITP) is a blood disorder in which antibodies coating platelets cause platelets destruction in the spleen with resultant low platelets count and an increased tendency for bleeding. Coronavirus disease 2019 (COVID-19) is an illness caused by SARS-COV2; it was first ide...

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Autores principales:	Hana Qasim, Elrazi Ali, Mohamad A. Yassin
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	ITP SARS-CoV-2 Pfizer vaccine Relapse Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/a41d23883e7c4084912c5bedd564c13f
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spelling	oai:doaj.org-article:a41d23883e7c4084912c5bedd564c13f2021-11-20T05:06:18ZImmune thrombocytopenia relapse post covid-19 vaccine in young male patient2214-250910.1016/j.idcr.2021.e01344https://doaj.org/article/a41d23883e7c4084912c5bedd564c13f2021-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2214250921003000https://doaj.org/toc/2214-2509Immune thrombocytopenic purpura (ITP) is a blood disorder in which antibodies coating platelets cause platelets destruction in the spleen with resultant low platelets count and an increased tendency for bleeding. Coronavirus disease 2019 (COVID-19) is an illness caused by SARS-COV2; it was first identified in December/2019; though it mainly affects the respiratory system, multisystemic complications are identified. Several ITP cases post mRNA SARS-CoV-2 vaccines were reported, and different pathophysiology theories about the underlying pathophysiology were discussed, but only a few ITP relapse cases have been reported so far. We present a 28-year-old Asian male, a known patient of ITP and in partial remission for eighteen months, who presented to the emergency department with ITP relapse (platelets count of 1 × 10^3 /µL), four days after receiving the second dose of Pfizer SARS-CoV-2 vaccine, which required treatment with intravenous immunoglobulins and dexamethasone. We further discuss the preferred approach in ITP patients who are willing to receive the COVID-19 vaccine.Hana QasimElrazi AliMohamad A. YassinElsevierarticleITPSARS-CoV-2Pfizer vaccineRelapseInfectious and parasitic diseasesRC109-216ENIDCases, Vol 26, Iss , Pp e01344- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	ITP SARS-CoV-2 Pfizer vaccine Relapse Infectious and parasitic diseases RC109-216
spellingShingle	ITP SARS-CoV-2 Pfizer vaccine Relapse Infectious and parasitic diseases RC109-216 Hana Qasim Elrazi Ali Mohamad A. Yassin Immune thrombocytopenia relapse post covid-19 vaccine in young male patient
description	Immune thrombocytopenic purpura (ITP) is a blood disorder in which antibodies coating platelets cause platelets destruction in the spleen with resultant low platelets count and an increased tendency for bleeding. Coronavirus disease 2019 (COVID-19) is an illness caused by SARS-COV2; it was first identified in December/2019; though it mainly affects the respiratory system, multisystemic complications are identified. Several ITP cases post mRNA SARS-CoV-2 vaccines were reported, and different pathophysiology theories about the underlying pathophysiology were discussed, but only a few ITP relapse cases have been reported so far. We present a 28-year-old Asian male, a known patient of ITP and in partial remission for eighteen months, who presented to the emergency department with ITP relapse (platelets count of 1 × 10^3 /µL), four days after receiving the second dose of Pfizer SARS-CoV-2 vaccine, which required treatment with intravenous immunoglobulins and dexamethasone. We further discuss the preferred approach in ITP patients who are willing to receive the COVID-19 vaccine.
format	article
author	Hana Qasim Elrazi Ali Mohamad A. Yassin
author_facet	Hana Qasim Elrazi Ali Mohamad A. Yassin
author_sort	Hana Qasim
title	Immune thrombocytopenia relapse post covid-19 vaccine in young male patient
title_short	Immune thrombocytopenia relapse post covid-19 vaccine in young male patient
title_full	Immune thrombocytopenia relapse post covid-19 vaccine in young male patient
title_fullStr	Immune thrombocytopenia relapse post covid-19 vaccine in young male patient
title_full_unstemmed	Immune thrombocytopenia relapse post covid-19 vaccine in young male patient
title_sort	immune thrombocytopenia relapse post covid-19 vaccine in young male patient
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/a41d23883e7c4084912c5bedd564c13f
work_keys_str_mv	AT hanaqasim immunethrombocytopeniarelapsepostcovid19vaccineinyoungmalepatient AT elraziali immunethrombocytopeniarelapsepostcovid19vaccineinyoungmalepatient AT mohamadayassin immunethrombocytopeniarelapsepostcovid19vaccineinyoungmalepatient
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Immune thrombocytopenia relapse post covid-19 vaccine in young male patient

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