When all you have is a dermatoscope—start looking at the nails

Pigmented and non-pigmented nail alterations are a frequent challenge for dermatologists. A profound knowledge of clinical and dermatoscopic features of nail disorders is crucial because a range of differential diagnoses and even potentially life-threatening diseases are possible underlying causes....

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Autores principales:	Holger A. Haenssle, Andreas Blum, Rainer Hofmann-Wellenhof, Juergen Kreusch, Wilhelm Stolz, Giuseppe Argenziano, Iris Zalaudek, Franziska Brehmer
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2014
Materias:	nail unit dermatoscoy melanoma nevus melanonychia striata acral pigmentation Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/a41f564a5c1d43bcbe6510b7851a553f
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spelling	oai:doaj.org-article:a41f564a5c1d43bcbe6510b7851a553f2021-11-17T08:31:58ZWhen all you have is a dermatoscope—start looking at the nails10.5826/dpc.0404a022160-9381https://doaj.org/article/a41f564a5c1d43bcbe6510b7851a553f2014-10-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/774https://doaj.org/toc/2160-9381 Pigmented and non-pigmented nail alterations are a frequent challenge for dermatologists. A profound knowledge of clinical and dermatoscopic features of nail disorders is crucial because a range of differential diagnoses and even potentially life-threatening diseases are possible underlying causes. Nail matrix melanocytes of unaffected individuals are in a dormant state, and, therefore, fingernails and toenails physiologically are non-pigmented. The formation of continuous, longitudinal pigmented streaks (longitudinal melanonychia) may either be caused by a benign activation of matrix melanocytes (e.g., as a result of trauma, inflammation, or adverse drug reactions) or by a true melanocytic proliferation (e.g., in a nevus or melanoma). In general, non-continuous nail alterations, affecting only limited parts of the nail apparatus, are most frequently of non-melanocytic origin. Important and common differential diagnoses in these cases are subungual hemorrhage or onychomycosis. In addition, foreign bodies, bacterial infections, traumatic injuries, or artificial discolorations of the nail unit may less frequently cause non-continuous nail alterations. Many systemic diseases that may also show involvement of the nails (e.g., psoriasis, atopic dermatitis, lichen planus, alopecia areata) tend to induce alterations in numerous if not all nails of the hands and feet. A similar extensive and generalized alteration of nails has been reported after treatment with a number of systemic drugs, especially antibiotics and cytostatics. Benign or malignant neoplasms that may also affect the nail unit include glomus tumor, Bowen’s disease, squamous cell carcinoma, and rare collision tumors. This review aims to assist clinicians in correctly evaluating and diagnosing nail disorders with the help of dermatoscopy. Holger A. HaenssleAndreas BlumRainer Hofmann-WellenhofJuergen KreuschWilhelm StolzGiuseppe ArgenzianoIris ZalaudekFranziska BrehmerMattioli1885articlenail unitdermatoscoymelanomanevusmelanonychia striataacral pigmentationDermatologyRL1-803ENDermatology Practical & Conceptual (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	nail unit dermatoscoy melanoma nevus melanonychia striata acral pigmentation Dermatology RL1-803
spellingShingle	nail unit dermatoscoy melanoma nevus melanonychia striata acral pigmentation Dermatology RL1-803 Holger A. Haenssle Andreas Blum Rainer Hofmann-Wellenhof Juergen Kreusch Wilhelm Stolz Giuseppe Argenziano Iris Zalaudek Franziska Brehmer When all you have is a dermatoscope—start looking at the nails
description	Pigmented and non-pigmented nail alterations are a frequent challenge for dermatologists. A profound knowledge of clinical and dermatoscopic features of nail disorders is crucial because a range of differential diagnoses and even potentially life-threatening diseases are possible underlying causes. Nail matrix melanocytes of unaffected individuals are in a dormant state, and, therefore, fingernails and toenails physiologically are non-pigmented. The formation of continuous, longitudinal pigmented streaks (longitudinal melanonychia) may either be caused by a benign activation of matrix melanocytes (e.g., as a result of trauma, inflammation, or adverse drug reactions) or by a true melanocytic proliferation (e.g., in a nevus or melanoma). In general, non-continuous nail alterations, affecting only limited parts of the nail apparatus, are most frequently of non-melanocytic origin. Important and common differential diagnoses in these cases are subungual hemorrhage or onychomycosis. In addition, foreign bodies, bacterial infections, traumatic injuries, or artificial discolorations of the nail unit may less frequently cause non-continuous nail alterations. Many systemic diseases that may also show involvement of the nails (e.g., psoriasis, atopic dermatitis, lichen planus, alopecia areata) tend to induce alterations in numerous if not all nails of the hands and feet. A similar extensive and generalized alteration of nails has been reported after treatment with a number of systemic drugs, especially antibiotics and cytostatics. Benign or malignant neoplasms that may also affect the nail unit include glomus tumor, Bowen’s disease, squamous cell carcinoma, and rare collision tumors. This review aims to assist clinicians in correctly evaluating and diagnosing nail disorders with the help of dermatoscopy.
format	article
author	Holger A. Haenssle Andreas Blum Rainer Hofmann-Wellenhof Juergen Kreusch Wilhelm Stolz Giuseppe Argenziano Iris Zalaudek Franziska Brehmer
author_facet	Holger A. Haenssle Andreas Blum Rainer Hofmann-Wellenhof Juergen Kreusch Wilhelm Stolz Giuseppe Argenziano Iris Zalaudek Franziska Brehmer
author_sort	Holger A. Haenssle
title	When all you have is a dermatoscope—start looking at the nails
title_short	When all you have is a dermatoscope—start looking at the nails
title_full	When all you have is a dermatoscope—start looking at the nails
title_fullStr	When all you have is a dermatoscope—start looking at the nails
title_full_unstemmed	When all you have is a dermatoscope—start looking at the nails
title_sort	when all you have is a dermatoscope—start looking at the nails
publisher	Mattioli1885
publishDate	2014
url	https://doaj.org/article/a41f564a5c1d43bcbe6510b7851a553f
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When all you have is a dermatoscope—start looking at the nails

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