A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus

Long non coding RNA molecules have been implicated in the immunopathology of a range of inflammatory pathologies. Here the authors show lncRNA MAARS regulates apoptosis via interaction with HuR in the context of atherosclerosis.

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Autores principales:	Viorel Simion, Haoyang Zhou, Stefan Haemmig, Jacob B. Pierce, Shanelle Mendes, Yevgenia Tesmenitsky, Daniel Pérez-Cremades, James F. Lee, Alex F. Chen, Nicoletta Ronda, Bianca Papotti, Jarrod A. Marto, Mark W. Feinberg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a42036a2b39749688a2059d2a4192cf7
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spelling	oai:doaj.org-article:a42036a2b39749688a2059d2a4192cf72021-12-02T16:56:34ZA macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus10.1038/s41467-020-19664-22041-1723https://doaj.org/article/a42036a2b39749688a2059d2a4192cf72020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19664-2https://doaj.org/toc/2041-1723Long non coding RNA molecules have been implicated in the immunopathology of a range of inflammatory pathologies. Here the authors show lncRNA MAARS regulates apoptosis via interaction with HuR in the context of atherosclerosis.Viorel SimionHaoyang ZhouStefan HaemmigJacob B. PierceShanelle MendesYevgenia TesmenitskyDaniel Pérez-CremadesJames F. LeeAlex F. ChenNicoletta RondaBianca PapottiJarrod A. MartoMark W. FeinbergNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Viorel Simion Haoyang Zhou Stefan Haemmig Jacob B. Pierce Shanelle Mendes Yevgenia Tesmenitsky Daniel Pérez-Cremades James F. Lee Alex F. Chen Nicoletta Ronda Bianca Papotti Jarrod A. Marto Mark W. Feinberg A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus
description	Long non coding RNA molecules have been implicated in the immunopathology of a range of inflammatory pathologies. Here the authors show lncRNA MAARS regulates apoptosis via interaction with HuR in the context of atherosclerosis.
format	article
author	Viorel Simion Haoyang Zhou Stefan Haemmig Jacob B. Pierce Shanelle Mendes Yevgenia Tesmenitsky Daniel Pérez-Cremades James F. Lee Alex F. Chen Nicoletta Ronda Bianca Papotti Jarrod A. Marto Mark W. Feinberg
author_facet	Viorel Simion Haoyang Zhou Stefan Haemmig Jacob B. Pierce Shanelle Mendes Yevgenia Tesmenitsky Daniel Pérez-Cremades James F. Lee Alex F. Chen Nicoletta Ronda Bianca Papotti Jarrod A. Marto Mark W. Feinberg
author_sort	Viorel Simion
title	A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus
title_short	A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus
title_full	A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus
title_fullStr	A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus
title_full_unstemmed	A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus
title_sort	macrophage-specific lncrna regulates apoptosis and atherosclerosis by tethering hur in the nucleus
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a42036a2b39749688a2059d2a4192cf7
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A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus

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