Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer

Male breast cancer (MBC) is rare and largely hormonally driven. Here, the authors examine the action of steroid hormone receptors in male and female breast cancers and find gender selective hormone receptor action that associates with the survival of MBC patients.

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Detalles Bibliográficos
Autores principales: Tesa M. Severson, Yongsoo Kim, Stacey E. P. Joosten, Karianne Schuurman, Petra van der Groep, Cathy B. Moelans, Natalie D. ter Hoeve, Quirine F. Manson, John W. Martens, Carolien H. M. van Deurzen, Ellis Barbe, Ingrid Hedenfalk, Peter Bult, Vincent T. H. B. M. Smit, Sabine C. Linn, Paul J. van Diest, Lodewyk Wessels, Wilbert Zwart
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/a437214d30c54971a83e6aa143ad69be
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Sumario:Male breast cancer (MBC) is rare and largely hormonally driven. Here, the authors examine the action of steroid hormone receptors in male and female breast cancers and find gender selective hormone receptor action that associates with the survival of MBC patients.