Reduced susceptibility of a Biomphalaria tenagophila population to Schistosoma mansoni after introducing the resistant Taim/RS strain of B. tenagophila into Herivelton Martins stream.

Studies performed in the last 30 years demonstrated that a strain of B. tenagophila from the Taim Biological Reserve is completely resistant to Schistosoma mansoni infection. This resistance to parasite infection is a dominant characteristic during crossbreeding with susceptible B. tenagophila strai...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Daisymara Priscila de Almeida Marques, Florence Mara Rosa, Engels Maciel, Deborah Negrão-Corrêa, Horácio Manuel Santana Teles, Roberta Lima Caldeira, Liana Konovaloff Jannotti-Passos, Paulo Marcos Zech Coelho
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a43b07c324fd4466963c5cfea8e3890c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a43b07c324fd4466963c5cfea8e3890c
record_format	dspace
spelling	oai:doaj.org-article:a43b07c324fd4466963c5cfea8e3890c2021-11-18T08:15:16ZReduced susceptibility of a Biomphalaria tenagophila population to Schistosoma mansoni after introducing the resistant Taim/RS strain of B. tenagophila into Herivelton Martins stream.1932-620310.1371/journal.pone.0099573https://doaj.org/article/a43b07c324fd4466963c5cfea8e3890c2014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24941324/?tool=EBIhttps://doaj.org/toc/1932-6203Studies performed in the last 30 years demonstrated that a strain of B. tenagophila from the Taim Biological Reserve is completely resistant to Schistosoma mansoni infection. This resistance to parasite infection is a dominant characteristic during crossbreeding with susceptible B. tenagophila strains. These experiments also identified a 350 bp molecular marker that is exclusive to the Taim strain and does not occur in other geographic strains of this snail species. The Taim strain (Taim/RS) of Biomphalaria tenagophila was bred on a large scale, physically marked and introduced into a stream in which previous malacological analyses had revealed the presence of only parasite-susceptible B. tenagophila. Samples of offspring captured 4, 11 and 14 months after the introduction of the Taim strain were examined, and the susceptibility of the snails to S. mansoni infection dropped from 38.6-26.5% to 2.1% during the 14 months after the introduction of the Taim snail strain. A significant correlation was also observed between the absence of infection and the identification of the Taim molecular marker. These results demonstrate that the genetic marker from the Taim strain was successfully introduced into the wild snail population. In addition, a significant relationship exists between the marker and resistance to infection.Daisymara Priscila de Almeida MarquesFlorence Mara RosaEngels MacielDeborah Negrão-CorrêaHorácio Manuel Santana TelesRoberta Lima CaldeiraLiana Konovaloff Jannotti-PassosPaulo Marcos Zech CoelhoPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 6, p e99573 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Daisymara Priscila de Almeida Marques Florence Mara Rosa Engels Maciel Deborah Negrão-Corrêa Horácio Manuel Santana Teles Roberta Lima Caldeira Liana Konovaloff Jannotti-Passos Paulo Marcos Zech Coelho Reduced susceptibility of a Biomphalaria tenagophila population to Schistosoma mansoni after introducing the resistant Taim/RS strain of B. tenagophila into Herivelton Martins stream.
description	Studies performed in the last 30 years demonstrated that a strain of B. tenagophila from the Taim Biological Reserve is completely resistant to Schistosoma mansoni infection. This resistance to parasite infection is a dominant characteristic during crossbreeding with susceptible B. tenagophila strains. These experiments also identified a 350 bp molecular marker that is exclusive to the Taim strain and does not occur in other geographic strains of this snail species. The Taim strain (Taim/RS) of Biomphalaria tenagophila was bred on a large scale, physically marked and introduced into a stream in which previous malacological analyses had revealed the presence of only parasite-susceptible B. tenagophila. Samples of offspring captured 4, 11 and 14 months after the introduction of the Taim strain were examined, and the susceptibility of the snails to S. mansoni infection dropped from 38.6-26.5% to 2.1% during the 14 months after the introduction of the Taim snail strain. A significant correlation was also observed between the absence of infection and the identification of the Taim molecular marker. These results demonstrate that the genetic marker from the Taim strain was successfully introduced into the wild snail population. In addition, a significant relationship exists between the marker and resistance to infection.
format	article
author	Daisymara Priscila de Almeida Marques Florence Mara Rosa Engels Maciel Deborah Negrão-Corrêa Horácio Manuel Santana Teles Roberta Lima Caldeira Liana Konovaloff Jannotti-Passos Paulo Marcos Zech Coelho
author_facet	Daisymara Priscila de Almeida Marques Florence Mara Rosa Engels Maciel Deborah Negrão-Corrêa Horácio Manuel Santana Teles Roberta Lima Caldeira Liana Konovaloff Jannotti-Passos Paulo Marcos Zech Coelho
author_sort	Daisymara Priscila de Almeida Marques
title	Reduced susceptibility of a Biomphalaria tenagophila population to Schistosoma mansoni after introducing the resistant Taim/RS strain of B. tenagophila into Herivelton Martins stream.
title_short	Reduced susceptibility of a Biomphalaria tenagophila population to Schistosoma mansoni after introducing the resistant Taim/RS strain of B. tenagophila into Herivelton Martins stream.
title_full	Reduced susceptibility of a Biomphalaria tenagophila population to Schistosoma mansoni after introducing the resistant Taim/RS strain of B. tenagophila into Herivelton Martins stream.
title_fullStr	Reduced susceptibility of a Biomphalaria tenagophila population to Schistosoma mansoni after introducing the resistant Taim/RS strain of B. tenagophila into Herivelton Martins stream.
title_full_unstemmed	Reduced susceptibility of a Biomphalaria tenagophila population to Schistosoma mansoni after introducing the resistant Taim/RS strain of B. tenagophila into Herivelton Martins stream.
title_sort	reduced susceptibility of a biomphalaria tenagophila population to schistosoma mansoni after introducing the resistant taim/rs strain of b. tenagophila into herivelton martins stream.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/a43b07c324fd4466963c5cfea8e3890c
work_keys_str_mv	AT daisymaraprisciladealmeidamarques reducedsusceptibilityofabiomphalariatenagophilapopulationtoschistosomamansoniafterintroducingtheresistanttaimrsstrainofbtenagophilaintoheriveltonmartinsstream AT florencemararosa reducedsusceptibilityofabiomphalariatenagophilapopulationtoschistosomamansoniafterintroducingtheresistanttaimrsstrainofbtenagophilaintoheriveltonmartinsstream AT engelsmaciel reducedsusceptibilityofabiomphalariatenagophilapopulationtoschistosomamansoniafterintroducingtheresistanttaimrsstrainofbtenagophilaintoheriveltonmartinsstream AT deborahnegraocorrea reducedsusceptibilityofabiomphalariatenagophilapopulationtoschistosomamansoniafterintroducingtheresistanttaimrsstrainofbtenagophilaintoheriveltonmartinsstream AT horaciomanuelsantanateles reducedsusceptibilityofabiomphalariatenagophilapopulationtoschistosomamansoniafterintroducingtheresistanttaimrsstrainofbtenagophilaintoheriveltonmartinsstream AT robertalimacaldeira reducedsusceptibilityofabiomphalariatenagophilapopulationtoschistosomamansoniafterintroducingtheresistanttaimrsstrainofbtenagophilaintoheriveltonmartinsstream AT lianakonovaloffjannottipassos reducedsusceptibilityofabiomphalariatenagophilapopulationtoschistosomamansoniafterintroducingtheresistanttaimrsstrainofbtenagophilaintoheriveltonmartinsstream AT paulomarcoszechcoelho reducedsusceptibilityofabiomphalariatenagophilapopulationtoschistosomamansoniafterintroducingtheresistanttaimrsstrainofbtenagophilaintoheriveltonmartinsstream
_version_	1718422001702404096

Reduced susceptibility of a Biomphalaria tenagophila population to Schistosoma mansoni after introducing the resistant Taim/RS strain of B. tenagophila into Herivelton Martins stream.

Ejemplares similares