Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity

Abstract Computational protein design has advanced very rapidly over the last decade, but there remain few examples of artificial proteins with direct medical applications. This study describes a new artificial β-trefoil lectin that recognises Burkitt’s lymphoma cells, and which was designed with th...

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Autores principales: Daiki Terada, Arnout R. D. Voet, Hiroki Noguchi, Kenichi Kamata, Mio Ohki, Christine Addy, Yuki Fujii, Daiki Yamamoto, Yasuhiro Ozeki, Jeremy R. H. Tame, Kam Y. J. Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/a440be7c963c4aa4b4ba9fc614b1d221
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