Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity

Abstract Computational protein design has advanced very rapidly over the last decade, but there remain few examples of artificial proteins with direct medical applications. This study describes a new artificial β-trefoil lectin that recognises Burkitt’s lymphoma cells, and which was designed with th...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Daiki Terada, Arnout R. D. Voet, Hiroki Noguchi, Kenichi Kamata, Mio Ohki, Christine Addy, Yuki Fujii, Daiki Yamamoto, Yasuhiro Ozeki, Jeremy R. H. Tame, Kam Y. J. Zhang
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/a440be7c963c4aa4b4ba9fc614b1d221
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!