Rescue of a H3N2 influenza virus containing a deficient neuraminidase protein by a hemagglutinin with a low receptor-binding affinity.

Influenza viruses possess at their surface two glycoproteins, the hemagglutinin and the neuraminidase, of which the antagonistic functions have to be well balanced for the virus to grow efficiently. Ferraris et al. isolated in 2003-2004 viruses lacking both a NA gene and protein (H3NA- viruses) (Fer...

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Autores principales: Mathilde Richard, Alexandra Erny, Bertrand Caré, Aurélien Traversier, Mendy Barthélémy, Alan Hay, Yi Pu Lin, Olivier Ferraris, Bruno Lina
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/a451aeeb15df4198b3532efb265f54e4
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