DETECTION OF CERTAIN GENETIC MARKERS OF THE PATHOGENIC FACTORS IN AUTOSTRAINS KLEBSIELLA SPP. IN INFANTS

The article presents the results of detection of genetic determinants of pathogenicity in 44 strains of Klebsiella (Klebsiella pneumoniae, Klebsiella oxytoca), isolated from the intestinal habitat of infants with intestinal dysbiosis. The presence of the uge gene was detected in 92 % of cases in K....

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Autores principales:	E. V. Bukharova, S. M. Popkova, E. B. Rakova, Y. P. Dhzioev, E. I. Ivanova, N. M. Shabanova, U. M. Nemchenko
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2014
Materias:	klebsiella spp intestinal microbiota pathogenicity genes pcr Science Q
Acceso en línea:	https://doaj.org/article/a458e610141e47de8ea3f22f78e9edac
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spelling	oai:doaj.org-article:a458e610141e47de8ea3f22f78e9edac2021-11-23T06:14:30ZDETECTION OF CERTAIN GENETIC MARKERS OF THE PATHOGENIC FACTORS IN AUTOSTRAINS KLEBSIELLA SPP. IN INFANTS2541-94202587-9596https://doaj.org/article/a458e610141e47de8ea3f22f78e9edac2014-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1739https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The article presents the results of detection of genetic determinants of pathogenicity in 44 strains of Klebsiella (Klebsiella pneumoniae, Klebsiella oxytoca), isolated from the intestinal habitat of infants with intestinal dysbiosis. The presence of the uge gene was detected in 92 % of cases in K. oxytoca and in 90 % of K. pneumoniae. Kfu gene was detected twice as frequent (30 %) in K. pneumoniae strains than in K. oxytoca (12,5 %); bfp gene was detected in K. oxytoca 5 times more frequently (25 %) than in K. pneumoniae (5 %), as well as stx 1 - 29,2 % and 15 %, correspondingly. The presence of stx 2 gene wasn't recorded in any of the DNA samples. Registration of investigated determinants in DNA of Klebsiella spp. autostrains which are non-clinical isolates indicates pathogenicity factors circulation among them and therefore the risk of the formation of intestinal dysbiosis in children.E. V. BukharovaS. M. PopkovaE. B. RakovaY. P. DhzioevE. I. IvanovaN. M. ShabanovaU. M. NemchenkoScientific Сentre for Family Health and Human Reproduction Problemsarticleklebsiella sppklebsiella sppintestinal microbiotapathogenicity genespcrScienceQRUActa Biomedica Scientifica, Vol 0, Iss 2, Pp 58-62 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	klebsiella spp klebsiella spp intestinal microbiota pathogenicity genes pcr Science Q
spellingShingle	klebsiella spp klebsiella spp intestinal microbiota pathogenicity genes pcr Science Q E. V. Bukharova S. M. Popkova E. B. Rakova Y. P. Dhzioev E. I. Ivanova N. M. Shabanova U. M. Nemchenko DETECTION OF CERTAIN GENETIC MARKERS OF THE PATHOGENIC FACTORS IN AUTOSTRAINS KLEBSIELLA SPP. IN INFANTS
description	The article presents the results of detection of genetic determinants of pathogenicity in 44 strains of Klebsiella (Klebsiella pneumoniae, Klebsiella oxytoca), isolated from the intestinal habitat of infants with intestinal dysbiosis. The presence of the uge gene was detected in 92 % of cases in K. oxytoca and in 90 % of K. pneumoniae. Kfu gene was detected twice as frequent (30 %) in K. pneumoniae strains than in K. oxytoca (12,5 %); bfp gene was detected in K. oxytoca 5 times more frequently (25 %) than in K. pneumoniae (5 %), as well as stx 1 - 29,2 % and 15 %, correspondingly. The presence of stx 2 gene wasn't recorded in any of the DNA samples. Registration of investigated determinants in DNA of Klebsiella spp. autostrains which are non-clinical isolates indicates pathogenicity factors circulation among them and therefore the risk of the formation of intestinal dysbiosis in children.
format	article
author	E. V. Bukharova S. M. Popkova E. B. Rakova Y. P. Dhzioev E. I. Ivanova N. M. Shabanova U. M. Nemchenko
author_facet	E. V. Bukharova S. M. Popkova E. B. Rakova Y. P. Dhzioev E. I. Ivanova N. M. Shabanova U. M. Nemchenko
author_sort	E. V. Bukharova
title	DETECTION OF CERTAIN GENETIC MARKERS OF THE PATHOGENIC FACTORS IN AUTOSTRAINS KLEBSIELLA SPP. IN INFANTS
title_short	DETECTION OF CERTAIN GENETIC MARKERS OF THE PATHOGENIC FACTORS IN AUTOSTRAINS KLEBSIELLA SPP. IN INFANTS
title_full	DETECTION OF CERTAIN GENETIC MARKERS OF THE PATHOGENIC FACTORS IN AUTOSTRAINS KLEBSIELLA SPP. IN INFANTS
title_fullStr	DETECTION OF CERTAIN GENETIC MARKERS OF THE PATHOGENIC FACTORS IN AUTOSTRAINS KLEBSIELLA SPP. IN INFANTS
title_full_unstemmed	DETECTION OF CERTAIN GENETIC MARKERS OF THE PATHOGENIC FACTORS IN AUTOSTRAINS KLEBSIELLA SPP. IN INFANTS
title_sort	detection of certain genetic markers of the pathogenic factors in autostrains klebsiella spp. in infants
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2014
url	https://doaj.org/article/a458e610141e47de8ea3f22f78e9edac
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DETECTION OF CERTAIN GENETIC MARKERS OF THE PATHOGENIC FACTORS IN AUTOSTRAINS KLEBSIELLA SPP. IN INFANTS

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