Selenium nanoparticles inhibit Staphylococcus aureus growth

Phong A Tran1, Thomas J Webster21Physics Department, 2School of Engineering and Department of Orthopedics, Brown University, Providence, RI, USAAbstract: Staphylococcus aureus is a key bacterium commonly found in numerous infections. S. aureus infections are difficult to treat due to their biofilm f...

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Autores principales:	Tran PA, Webster TJ
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/a45a83b2dbbe4b598c8b21cdcef463d9
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spelling	oai:doaj.org-article:a45a83b2dbbe4b598c8b21cdcef463d92021-12-02T01:42:37ZSelenium nanoparticles inhibit Staphylococcus aureus growth1176-91141178-2013https://doaj.org/article/a45a83b2dbbe4b598c8b21cdcef463d92011-07-01T00:00:00Zhttp://www.dovepress.com/selenium-nanoparticles-inhibit-staphylococcus-aureus-growth-a7986https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Phong A Tran1, Thomas J Webster21Physics Department, 2School of Engineering and Department of Orthopedics, Brown University, Providence, RI, USAAbstract: Staphylococcus aureus is a key bacterium commonly found in numerous infections. S. aureus infections are difficult to treat due to their biofilm formation and documented antibiotic resistance. While selenium has been used for a wide range of applications including anticancer applications, the effects of selenium nanoparticles on microorganisms remain largely unknown to date. The objective of this in vitro study was thus to examine the growth of S. aureus in the presence of selenium nanoparticles. Results of this study provided the first evidence of strongly inhibited growth of S. aureus in the presence of selenium nanoparticles after 3, 4, and 5 hours at 7.8, 15.5, and 31 &micro;g/mL. The percentage of live bacteria also decreased in the presence of selenium nanoparticles. Therefore, this study suggests that selenium nanoparticles may be used to effectively prevent and treat S. aureus infections and thus should be further studied for such applications.Keywords: antibacterial, S. aureus, infection&nbsp;Tran PAWebster TJDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2011, Iss default, Pp 1553-1558 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Tran PA Webster TJ Selenium nanoparticles inhibit Staphylococcus aureus growth
description	Phong A Tran1, Thomas J Webster21Physics Department, 2School of Engineering and Department of Orthopedics, Brown University, Providence, RI, USAAbstract: Staphylococcus aureus is a key bacterium commonly found in numerous infections. S. aureus infections are difficult to treat due to their biofilm formation and documented antibiotic resistance. While selenium has been used for a wide range of applications including anticancer applications, the effects of selenium nanoparticles on microorganisms remain largely unknown to date. The objective of this in vitro study was thus to examine the growth of S. aureus in the presence of selenium nanoparticles. Results of this study provided the first evidence of strongly inhibited growth of S. aureus in the presence of selenium nanoparticles after 3, 4, and 5 hours at 7.8, 15.5, and 31 &micro;g/mL. The percentage of live bacteria also decreased in the presence of selenium nanoparticles. Therefore, this study suggests that selenium nanoparticles may be used to effectively prevent and treat S. aureus infections and thus should be further studied for such applications.Keywords: antibacterial, S. aureus, infection&nbsp;
format	article
author	Tran PA Webster TJ
author_facet	Tran PA Webster TJ
author_sort	Tran PA
title	Selenium nanoparticles inhibit Staphylococcus aureus growth
title_short	Selenium nanoparticles inhibit Staphylococcus aureus growth
title_full	Selenium nanoparticles inhibit Staphylococcus aureus growth
title_fullStr	Selenium nanoparticles inhibit Staphylococcus aureus growth
title_full_unstemmed	Selenium nanoparticles inhibit Staphylococcus aureus growth
title_sort	selenium nanoparticles inhibit staphylococcus aureus growth
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/a45a83b2dbbe4b598c8b21cdcef463d9
work_keys_str_mv	AT tranpa seleniumnanoparticlesinhibitstaphylococcusaureusgrowth AT webstertj seleniumnanoparticlesinhibitstaphylococcusaureusgrowth
_version_	1718402912484327424

Selenium nanoparticles inhibit Staphylococcus aureus growth

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