WNT/β-Catenin Pathway in Soft Tissue Sarcomas: New Therapeutic Opportunities?

Código QR

WNT/β-Catenin Pathway in Soft Tissue Sarcomas: New Therapeutic Opportunities?

Soft tissue sarcomas (STS) are a very heterogeneous group of rare tumors, comprising more than 50 different histological subtypes that originate from mesenchymal tissue. Despite their heterogeneity, chemotherapy based on doxorubicin (DXR) has been in use for forty years now and remains the standard...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Esther Martinez-Font, Marina Pérez-Capó, Oliver Vögler, Javier Martín-Broto, Regina Alemany, Antònia Obrador-Hevia
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	soft tissue sarcoma WNT signaling β-catenin Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/a45dc9a8d91e4650bb49e2236ccc4c4f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

ROLE OF GSK-3 IN Wnt/β-CATENIN SIGNALING PATHWAY IN OBESITY
por: A. S. Kulakova, et al.
Publicado: (2021)

FERMT3 mediates cigarette smoke-induced epithelial–mesenchymal transition through Wnt/β-catenin signaling
por: Xiaoshan Su, et al.
Publicado: (2021)

CXCL14 facilitates the growth and metastasis of ovarian carcinoma cells via activation of the Wnt/β-catenin signaling pathway
por: Li-Na Gao, et al.
Publicado: (2021)

Wnt/β-Catenin Pathway in Experimental Model of Fibromyalgia: Role of Hidrox<sup>®</sup>
por: Ramona D’Amico, et al.
Publicado: (2021)

Expression of Wnt and β-Catenin in Mouse Tooth Germs and Chick Facial Primordia: A Comparison
por: Louryan,S., et al.
Publicado: (2018)

WDR74 promotes proliferation and metastasis in colorectal cancer cells through regulating the Wnt/β-catenin signaling pathway
por: Cai Zhou, et al.
Publicado: (2021)

Imaging and Pathological Features of Alveolar Soft Part Sarcoma: Analysis of 16 Patients
por: Malvika Gulati, et al.
Publicado: (2021)

Maternal Swimming Exercise During Pregnancy Improves Memory Through Enhancing Neurogenesis and Suppressing Apoptosis via Wnt/β-Catenin Pathway in Autistic Mice
por: Sang-Seo Park, et al.
Publicado: (2021)

Chronic Circadian Rhythm Disturbance Accelerates Knee Cartilage Degeneration in Rats Accompanied by the Activation of the Canonical Wnt/β-Catenin Signaling Pathway
por: Xiaopeng Song, et al.
Publicado: (2021)

LncRNA CASC11 promotes the cervical cancer progression by activating Wnt/beta-catenin signaling pathway
por: Hsu,Wenchan, et al.
Publicado: (2019)

Wnt/β-Catenin-Dependent Transcription in Autism Spectrum Disorders
por: Mario O. Caracci, et al.
Publicado: (2021)

Demographics, Changes in Treatment Patterns, and Outcomes of Bone and Soft Tissue Sarcomas in Korea—A Sarcoma-Specific, Institutional Registry-Based Analysis
por: Jeong H, et al.
Publicado: (2021)

The Key Role of the WNT/β-Catenin Pathway in Metabolic Reprogramming in Cancers under Normoxic Conditions
por: Alexandre Vallée, et al.
Publicado: (2021)

FOXA1 Suppresses SATB1 Transcription and Inactivates the Wnt/β-Catenin Pathway to Alleviate Diabetic Nephropathy in a Mouse Model
por: Zhu H, et al.
Publicado: (2021)

PM2.5 Induces Airway Remodeling in Chronic Obstructive Pulmonary Diseases via the Wnt5a/β-Catenin Pathway
por: Zou W, et al.
Publicado: (2021)

Super-enhancer-driven lncRNA-DAW promotes liver cancer cell proliferation through activation of Wnt/β-catenin pathway
por: Weicheng Liang, et al.
Publicado: (2021)

Does the Use of Peripheral Immune-Related Markers Indicate Whether to Administer Pazopanib, Trabectedin, or Eribulin to Advanced Soft Tissue Sarcoma Patients?
por: Eijiro Shimada, et al.
Publicado: (2021)

miR-142-5p promotes cervical cancer progression by targeting LMX1A through Wnt/β-catenin pathway
por: Ke Lijuan, et al.
Publicado: (2021)

Review: The Role of Wnt/β-Catenin Signalling in Neural Crest Development in Zebrafish
por: Gemma Sutton, et al.
Publicado: (2021)

Identification and Validation of a Novel Pyroptosis-Related Gene Signature for Prognosis Prediction in Soft Tissue Sarcoma
por: Lin Qi, et al.
Publicado: (2021)

Novel lncRNA LINC01614 Facilitates Bladder Cancer Proliferation, Migration and Invasion Through the miR-217/RUNX2/Wnt/β-Catenin Axis
por: Wang Z, et al.
Publicado: (2021)

Functional Recellularization of Acellular Rat Liver Scaffold by Induced Pluripotent Stem Cells: Molecular Evidence for Wnt/B-Catenin Upregulation
por: Nesrine Ebrahim, et al.
Publicado: (2021)

Identification and Validation of Pyroptosis-Related lncRNA Signature and Its Correlation with Immune Landscape in Soft Tissue Sarcomas
por: Lin Z, et al.
Publicado: (2021)

Venlafaxine Inhibits the Apoptosis of SHSY-5Y Cells Through Active Wnt/β-Catenin Signaling Pathway
por: Geng R, et al.
Publicado: (2021)

Cellular retinol binding protein-1 inhibits cancer stemness via upregulating WIF1 to suppress Wnt/β-catenin pathway in hepatocellular carcinoma
por: Xiangye Liu, et al.
Publicado: (2021)

CCR9 initiates epithelial–mesenchymal transition by activating Wnt/β-catenin pathways to promote osteosarcoma metastasis
por: Haoran Kong, et al.
Publicado: (2021)

Sclerostin and Its Involvement in the Pathogenesis of Idiopathic Scoliosis
por: Elias S. Vasiliadis, et al.
Publicado: (2021)

miR-214 ameliorates acute kidney injury via targeting DKK3 and activating of Wnt/β-catenin signaling pathway
por: Zhu,Xiaoguang, et al.
Publicado: (2018)

Inhibition of the immunoproteasome LMP2 ameliorates ischemia/hypoxia-induced blood–brain barrier injury through the Wnt/β-catenin signalling pathway
por: Xing-Yong Chen, et al.
Publicado: (2021)

A novel mutation of SATB2 inhibits odontogenesis of human dental pulp stem cells through Wnt/β-catenin signaling pathway
por: Tianyi Xin, et al.
Publicado: (2021)

Substrate Stiffness Drives Epithelial to Mesenchymal Transition and Proliferation through the <i>NEAT1</i>-Wnt/β-Catenin Pathway in Liver Cancer
por: Xichao Xu, et al.
Publicado: (2021)

β-Catenin: oncogenic role and therapeutic target in cervical cancer
por: Wang,Bingqi, et al.
Publicado: (2020)

A Novel Four-Gene Prognostic Signature for Prediction of Survival in Patients with Soft Tissue Sarcoma
por: Changwu Wu, et al.
Publicado: (2021)

MicroRNA-22-3p targeted regulating transcription factor 7-like 2 (TCF7L2) constrains the Wnt/β-catenin pathway and malignant behavior in osteosarcoma
por: YuanLiang Xue, et al.
Publicado: (2021)

Molecular profiling of advanced soft-tissue sarcomas: the MULTISARC randomized trial
por: Antoine Italiano, et al.
Publicado: (2021)

Ethionine-mediated reduction of S-adenosylmethionine is responsible for the neural tube defects in the developing mouse embryo-mediated m6A modification and is involved in neural tube defects via modulating Wnt/β-catenin signaling pathway
por: Li Zhang, et al.
Publicado: (2021)

Exogenous Wnt1 Prevents Acute Kidney Injury and Its Subsequent Progression to Chronic Kidney Disease
por: Xue Hong, et al.
Publicado: (2021)

Long noncoding RNA CASC2 predicts the prognosis of glioma patients and functions as a suppressor for gliomas by suppressing Wnt/β-catenin signaling pathway
por: Wang R, et al.
Publicado: (2017)

GSK3-beta as a candidate therapeutic target in soft tissue sarcomas
por: S. Verbeke, et al.
Publicado: (2021)

Establishment of A Nomogram for Predicting the Prognosis of Soft Tissue Sarcoma Based on Seven Glycolysis-Related Gene Risk Score
por: Yuhang Liu, et al.
Publicado: (2021)