scGNN is a novel graph neural network framework for single-cell RNA-Seq analyses
Single-cell RNA-Seq suffers from heterogeneity in sequencing sparsity and complex differential patterns in gene expression. Here, the authors introduce a graph neural network based on a hypothesis-free deep learning framework as an effective representation of gene expression and cell–cell relationsh...
Guardado en:
Autores principales: | , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/a461a5e31f27497ea7c1e605964bab0a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:a461a5e31f27497ea7c1e605964bab0a |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:a461a5e31f27497ea7c1e605964bab0a2021-12-02T11:44:56ZscGNN is a novel graph neural network framework for single-cell RNA-Seq analyses10.1038/s41467-021-22197-x2041-1723https://doaj.org/article/a461a5e31f27497ea7c1e605964bab0a2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22197-xhttps://doaj.org/toc/2041-1723Single-cell RNA-Seq suffers from heterogeneity in sequencing sparsity and complex differential patterns in gene expression. Here, the authors introduce a graph neural network based on a hypothesis-free deep learning framework as an effective representation of gene expression and cell–cell relationships.Juexin WangAnjun MaYuzhou ChangJianting GongYuexu JiangRen QiCankun WangHongjun FuQin MaDong XuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Juexin Wang Anjun Ma Yuzhou Chang Jianting Gong Yuexu Jiang Ren Qi Cankun Wang Hongjun Fu Qin Ma Dong Xu scGNN is a novel graph neural network framework for single-cell RNA-Seq analyses |
description |
Single-cell RNA-Seq suffers from heterogeneity in sequencing sparsity and complex differential patterns in gene expression. Here, the authors introduce a graph neural network based on a hypothesis-free deep learning framework as an effective representation of gene expression and cell–cell relationships. |
format |
article |
author |
Juexin Wang Anjun Ma Yuzhou Chang Jianting Gong Yuexu Jiang Ren Qi Cankun Wang Hongjun Fu Qin Ma Dong Xu |
author_facet |
Juexin Wang Anjun Ma Yuzhou Chang Jianting Gong Yuexu Jiang Ren Qi Cankun Wang Hongjun Fu Qin Ma Dong Xu |
author_sort |
Juexin Wang |
title |
scGNN is a novel graph neural network framework for single-cell RNA-Seq analyses |
title_short |
scGNN is a novel graph neural network framework for single-cell RNA-Seq analyses |
title_full |
scGNN is a novel graph neural network framework for single-cell RNA-Seq analyses |
title_fullStr |
scGNN is a novel graph neural network framework for single-cell RNA-Seq analyses |
title_full_unstemmed |
scGNN is a novel graph neural network framework for single-cell RNA-Seq analyses |
title_sort |
scgnn is a novel graph neural network framework for single-cell rna-seq analyses |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/a461a5e31f27497ea7c1e605964bab0a |
work_keys_str_mv |
AT juexinwang scgnnisanovelgraphneuralnetworkframeworkforsinglecellrnaseqanalyses AT anjunma scgnnisanovelgraphneuralnetworkframeworkforsinglecellrnaseqanalyses AT yuzhouchang scgnnisanovelgraphneuralnetworkframeworkforsinglecellrnaseqanalyses AT jiantinggong scgnnisanovelgraphneuralnetworkframeworkforsinglecellrnaseqanalyses AT yuexujiang scgnnisanovelgraphneuralnetworkframeworkforsinglecellrnaseqanalyses AT renqi scgnnisanovelgraphneuralnetworkframeworkforsinglecellrnaseqanalyses AT cankunwang scgnnisanovelgraphneuralnetworkframeworkforsinglecellrnaseqanalyses AT hongjunfu scgnnisanovelgraphneuralnetworkframeworkforsinglecellrnaseqanalyses AT qinma scgnnisanovelgraphneuralnetworkframeworkforsinglecellrnaseqanalyses AT dongxu scgnnisanovelgraphneuralnetworkframeworkforsinglecellrnaseqanalyses |
_version_ |
1718395301455200256 |