Factors related to the spontaneous passage of common bile duct stones through the papilla: a single-center retrospective cohort study

Objective Common bile duct (CBD) stones can spontaneously pass through the papilla. This study explored factors associated with stone passage by comparing differences in the clinical features of stones retained in the CBD and excreted stones. Methods Data were retrospectively collected for all patie...

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Autores principales:	Songming Ding, Shanjie Dong, Hengkai Zhu, Weilin Wu, Yiting Hu, Qiyong Li, Shusen Zheng
Formato:	article
Lenguaje:	EN
Publicado:	SAGE Publishing 2021
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/a465b0a7eff24295bf3b35896b049f8a
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spelling	oai:doaj.org-article:a465b0a7eff24295bf3b35896b049f8a2021-11-18T01:03:32ZFactors related to the spontaneous passage of common bile duct stones through the papilla: a single-center retrospective cohort study1473-230010.1177/03000605211058381https://doaj.org/article/a465b0a7eff24295bf3b35896b049f8a2021-11-01T00:00:00Zhttps://doi.org/10.1177/03000605211058381https://doaj.org/toc/1473-2300Objective Common bile duct (CBD) stones can spontaneously pass through the papilla. This study explored factors associated with stone passage by comparing differences in the clinical features of stones retained in the CBD and excreted stones. Methods Data were retrospectively collected for all patients who were hospitalized in our center between March 2016 and May 2021 with clinical, laboratory, or imaging evidence of CBD stones. All patients underwent endoscopic retrograde cholangiopancreatography (ERCP) and were classified into two groups: group A (stones extracted by ERCP, n = 86) and group B (stones discharged before ERCP, n = 15). Demographic data, biochemical and radiological findings were compared between the groups. Results Stone size (0.82 vs. 0.33 cm), and levels of total bilirubin (58.2 vs. 28.8 μmol/L), gamma-glutamyl transpeptidase (416.7 vs. 193.9 U/L), alkaline phosphatase (191.9 vs. 123.1 U/L), carbohydrate antigen 19-9 (603.7 vs. 37.2 U/mL), and α-L-fucosidase (37.4 vs. 22.6 U/L) were significantly higher in group A than in group B. Logistic regression analyses showed that stone size was the only factor significantly associated with spontaneous passage of CBD stones. Conclusions CBD stones less than 0.33 cm in size may be self-expelled through the papilla.Songming DingShanjie DongHengkai ZhuWeilin WuYiting HuQiyong LiShusen ZhengSAGE PublishingarticleMedicine (General)R5-920ENJournal of International Medical Research, Vol 49 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Songming Ding Shanjie Dong Hengkai Zhu Weilin Wu Yiting Hu Qiyong Li Shusen Zheng Factors related to the spontaneous passage of common bile duct stones through the papilla: a single-center retrospective cohort study
description	Objective Common bile duct (CBD) stones can spontaneously pass through the papilla. This study explored factors associated with stone passage by comparing differences in the clinical features of stones retained in the CBD and excreted stones. Methods Data were retrospectively collected for all patients who were hospitalized in our center between March 2016 and May 2021 with clinical, laboratory, or imaging evidence of CBD stones. All patients underwent endoscopic retrograde cholangiopancreatography (ERCP) and were classified into two groups: group A (stones extracted by ERCP, n = 86) and group B (stones discharged before ERCP, n = 15). Demographic data, biochemical and radiological findings were compared between the groups. Results Stone size (0.82 vs. 0.33 cm), and levels of total bilirubin (58.2 vs. 28.8 μmol/L), gamma-glutamyl transpeptidase (416.7 vs. 193.9 U/L), alkaline phosphatase (191.9 vs. 123.1 U/L), carbohydrate antigen 19-9 (603.7 vs. 37.2 U/mL), and α-L-fucosidase (37.4 vs. 22.6 U/L) were significantly higher in group A than in group B. Logistic regression analyses showed that stone size was the only factor significantly associated with spontaneous passage of CBD stones. Conclusions CBD stones less than 0.33 cm in size may be self-expelled through the papilla.
format	article
author	Songming Ding Shanjie Dong Hengkai Zhu Weilin Wu Yiting Hu Qiyong Li Shusen Zheng
author_facet	Songming Ding Shanjie Dong Hengkai Zhu Weilin Wu Yiting Hu Qiyong Li Shusen Zheng
author_sort	Songming Ding
title	Factors related to the spontaneous passage of common bile duct stones through the papilla: a single-center retrospective cohort study
title_short	Factors related to the spontaneous passage of common bile duct stones through the papilla: a single-center retrospective cohort study
title_full	Factors related to the spontaneous passage of common bile duct stones through the papilla: a single-center retrospective cohort study
title_fullStr	Factors related to the spontaneous passage of common bile duct stones through the papilla: a single-center retrospective cohort study
title_full_unstemmed	Factors related to the spontaneous passage of common bile duct stones through the papilla: a single-center retrospective cohort study
title_sort	factors related to the spontaneous passage of common bile duct stones through the papilla: a single-center retrospective cohort study
publisher	SAGE Publishing
publishDate	2021
url	https://doaj.org/article/a465b0a7eff24295bf3b35896b049f8a
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Factors related to the spontaneous passage of common bile duct stones through the papilla: a single-center retrospective cohort study

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