Mortality and medical care after bereavement: a general practice cohort study.

Bereaved spouses or partners are thought to be at increased risk of morbidity and mortality. However, there are few large prospective studies and results are inconsistent. We estimated the relative mortality, prescription of psychotropic medication and use of primary medical care services in adults...

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Autores principales: Michael King, Mira Vasanthan, Irene Petersen, Louise Jones, Louise Marston, Irwin Nazareth
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Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/a4673aef2f5448fdad2eee639e4f2b68
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spelling oai:doaj.org-article:a4673aef2f5448fdad2eee639e4f2b682021-11-18T07:59:50ZMortality and medical care after bereavement: a general practice cohort study.1932-620310.1371/journal.pone.0052561https://doaj.org/article/a4673aef2f5448fdad2eee639e4f2b682013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23372651/?tool=EBIhttps://doaj.org/toc/1932-6203Bereaved spouses or partners are thought to be at increased risk of morbidity and mortality. However, there are few large prospective studies and results are inconsistent. We estimated the relative mortality, prescription of psychotropic medication and use of primary medical care services in adults whose cohabitee died of cancer. To do this, we undertook a cohort study using The Health Improvement Network (THIN) UK primary care database. Participants were 1) people aged over 40, who were registered with general practices and had been exposed to the death of a cohabitee from cancer; and 2) a comparison cohort frequency matched on five year age bands and sex who were cohabiting with a living partner. The baseline was chosen as six months before the date of the cancer death for the exposed group and a random date for the unexposed group. Incidence rate ratios (IRR) with 95% confidence intervals (CI) were estimated using random effects Poisson regression to account for clustering within general practices and adjusting for other key variables. 92,129 patients were studied for a median follow up of 4 years. Cohabitees of patients who died of cancer were less likely to die of any cause (IRR 0.71, CI 0.68-0.74) after adjustment for age, gender, number of non-psychotropic prescriptions 6 months before the cancer death/index date, use of psychotropic medication 6 months before the cancer death/index date, smoking, alcohol and area deprivation score. Exposed patients were more likely to receive a prescription for antidepressant or hypnotic medication and to attend their GP both before and after the death of the cohabitee. In conclusion, we did not confirm increased mortality in cohabitees of people dying from cancer.Michael KingMira VasanthanIrene PetersenLouise JonesLouise MarstonIrwin NazarethPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 1, p e52561 (2013)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Michael King
Mira Vasanthan
Irene Petersen
Louise Jones
Louise Marston
Irwin Nazareth
Mortality and medical care after bereavement: a general practice cohort study.
description Bereaved spouses or partners are thought to be at increased risk of morbidity and mortality. However, there are few large prospective studies and results are inconsistent. We estimated the relative mortality, prescription of psychotropic medication and use of primary medical care services in adults whose cohabitee died of cancer. To do this, we undertook a cohort study using The Health Improvement Network (THIN) UK primary care database. Participants were 1) people aged over 40, who were registered with general practices and had been exposed to the death of a cohabitee from cancer; and 2) a comparison cohort frequency matched on five year age bands and sex who were cohabiting with a living partner. The baseline was chosen as six months before the date of the cancer death for the exposed group and a random date for the unexposed group. Incidence rate ratios (IRR) with 95% confidence intervals (CI) were estimated using random effects Poisson regression to account for clustering within general practices and adjusting for other key variables. 92,129 patients were studied for a median follow up of 4 years. Cohabitees of patients who died of cancer were less likely to die of any cause (IRR 0.71, CI 0.68-0.74) after adjustment for age, gender, number of non-psychotropic prescriptions 6 months before the cancer death/index date, use of psychotropic medication 6 months before the cancer death/index date, smoking, alcohol and area deprivation score. Exposed patients were more likely to receive a prescription for antidepressant or hypnotic medication and to attend their GP both before and after the death of the cohabitee. In conclusion, we did not confirm increased mortality in cohabitees of people dying from cancer.
format article
author Michael King
Mira Vasanthan
Irene Petersen
Louise Jones
Louise Marston
Irwin Nazareth
author_facet Michael King
Mira Vasanthan
Irene Petersen
Louise Jones
Louise Marston
Irwin Nazareth
author_sort Michael King
title Mortality and medical care after bereavement: a general practice cohort study.
title_short Mortality and medical care after bereavement: a general practice cohort study.
title_full Mortality and medical care after bereavement: a general practice cohort study.
title_fullStr Mortality and medical care after bereavement: a general practice cohort study.
title_full_unstemmed Mortality and medical care after bereavement: a general practice cohort study.
title_sort mortality and medical care after bereavement: a general practice cohort study.
publisher Public Library of Science (PLoS)
publishDate 2013
url https://doaj.org/article/a4673aef2f5448fdad2eee639e4f2b68
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