Enhanced proliferation of rabbit chondrocytes by using a well circulated nanoshock system

Abstract The gold nanorods (GNRs) embedded alginate-chitosan (scaffold), which was designed and fabricated to produce efficient handling of the cell proliferations. Scaffold embedded GNR (SGNR) and NIR (near infrared) irradiations are developing into an interesting medical prognosis tool for rabbit...

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Autores principales:	Sitansu Sekhar Nanda, Tuntun Wang, Hong Yeol Yoon, Seong Soo A. An, K. P. S. S. Hembram, Kwangmeyung Kim, Dong Kee Yi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a4700e8691d04122b1c83b6141fa3598
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spelling	oai:doaj.org-article:a4700e8691d04122b1c83b6141fa35982021-12-02T17:17:39ZEnhanced proliferation of rabbit chondrocytes by using a well circulated nanoshock system10.1038/s41598-021-98929-22045-2322https://doaj.org/article/a4700e8691d04122b1c83b6141fa35982021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-98929-2https://doaj.org/toc/2045-2322Abstract The gold nanorods (GNRs) embedded alginate-chitosan (scaffold), which was designed and fabricated to produce efficient handling of the cell proliferations. Scaffold embedded GNR (SGNR) and NIR (near infrared) irradiations are developing into an interesting medical prognosis tool for rabbit chondrocyte (RC) proliferation. SGNR contained a pattern of uniform pores. Biocompatibility and cellular proliferation achieved by disclosures to NIR irradiations, providing high cell survival. SGNR and NIR irradiations could produce mechanical and biochemical cues for regulating RCs proliferations. To determine the thermal stress, it exposed RCs to 39–42 °C for 0–240 min at the start point of the cell culture cycle. It produced photothermal stress in cellular surrounding (cells located adjacent to and within scaffold) and it deals with the proliferation behavior of RC. All the processes were modeled with experimental criteria and time evolution process. Our system could help the cell proliferation by generating heat for cells. Hence, the present strategy could be implemented for supporting cell therapeutics after transplantation. This implementation would open new design techniques for integrating the interfaces between NIR irradiated and non-irradiated tissues.Sitansu Sekhar NandaTuntun WangHong Yeol YoonSeong Soo A. AnK. P. S. S. HembramKwangmeyung KimDong Kee YiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Sitansu Sekhar Nanda Tuntun Wang Hong Yeol Yoon Seong Soo A. An K. P. S. S. Hembram Kwangmeyung Kim Dong Kee Yi Enhanced proliferation of rabbit chondrocytes by using a well circulated nanoshock system
description	Abstract The gold nanorods (GNRs) embedded alginate-chitosan (scaffold), which was designed and fabricated to produce efficient handling of the cell proliferations. Scaffold embedded GNR (SGNR) and NIR (near infrared) irradiations are developing into an interesting medical prognosis tool for rabbit chondrocyte (RC) proliferation. SGNR contained a pattern of uniform pores. Biocompatibility and cellular proliferation achieved by disclosures to NIR irradiations, providing high cell survival. SGNR and NIR irradiations could produce mechanical and biochemical cues for regulating RCs proliferations. To determine the thermal stress, it exposed RCs to 39–42 °C for 0–240 min at the start point of the cell culture cycle. It produced photothermal stress in cellular surrounding (cells located adjacent to and within scaffold) and it deals with the proliferation behavior of RC. All the processes were modeled with experimental criteria and time evolution process. Our system could help the cell proliferation by generating heat for cells. Hence, the present strategy could be implemented for supporting cell therapeutics after transplantation. This implementation would open new design techniques for integrating the interfaces between NIR irradiated and non-irradiated tissues.
format	article
author	Sitansu Sekhar Nanda Tuntun Wang Hong Yeol Yoon Seong Soo A. An K. P. S. S. Hembram Kwangmeyung Kim Dong Kee Yi
author_facet	Sitansu Sekhar Nanda Tuntun Wang Hong Yeol Yoon Seong Soo A. An K. P. S. S. Hembram Kwangmeyung Kim Dong Kee Yi
author_sort	Sitansu Sekhar Nanda
title	Enhanced proliferation of rabbit chondrocytes by using a well circulated nanoshock system
title_short	Enhanced proliferation of rabbit chondrocytes by using a well circulated nanoshock system
title_full	Enhanced proliferation of rabbit chondrocytes by using a well circulated nanoshock system
title_fullStr	Enhanced proliferation of rabbit chondrocytes by using a well circulated nanoshock system
title_full_unstemmed	Enhanced proliferation of rabbit chondrocytes by using a well circulated nanoshock system
title_sort	enhanced proliferation of rabbit chondrocytes by using a well circulated nanoshock system
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a4700e8691d04122b1c83b6141fa3598
work_keys_str_mv	AT sitansusekharnanda enhancedproliferationofrabbitchondrocytesbyusingawellcirculatednanoshocksystem AT tuntunwang enhancedproliferationofrabbitchondrocytesbyusingawellcirculatednanoshocksystem AT hongyeolyoon enhancedproliferationofrabbitchondrocytesbyusingawellcirculatednanoshocksystem AT seongsooaan enhancedproliferationofrabbitchondrocytesbyusingawellcirculatednanoshocksystem AT kpsshembram enhancedproliferationofrabbitchondrocytesbyusingawellcirculatednanoshocksystem AT kwangmeyungkim enhancedproliferationofrabbitchondrocytesbyusingawellcirculatednanoshocksystem AT dongkeeyi enhancedproliferationofrabbitchondrocytesbyusingawellcirculatednanoshocksystem
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Enhanced proliferation of rabbit chondrocytes by using a well circulated nanoshock system

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