Risk of severe knee and hip osteoarthritis in relation to level of physical exercise: a prospective cohort study of long-distance skiers in Sweden.

<h4>Background</h4>To complete long-distance ski races, regular physical exercise is required. This includes not only cross-country skiing but also endurance exercise during the snow-free seasons. The aim of this study was to determine whether the level of physical exercise is associated...

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Autores principales:	Karl Michaëlsson, Liisa Byberg, Anders Ahlbom, Håkan Melhus, Bahman Y Farahmand
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2011
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a4719a59ba064531a6dd781f78a2fc0b
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spelling	oai:doaj.org-article:a4719a59ba064531a6dd781f78a2fc0b2021-11-18T06:56:35ZRisk of severe knee and hip osteoarthritis in relation to level of physical exercise: a prospective cohort study of long-distance skiers in Sweden.1932-620310.1371/journal.pone.0018339https://doaj.org/article/a4719a59ba064531a6dd781f78a2fc0b2011-03-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21479136/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>To complete long-distance ski races, regular physical exercise is required. This includes not only cross-country skiing but also endurance exercise during the snow-free seasons. The aim of this study was to determine whether the level of physical exercise is associated with future risk of severe osteoarthritis independent of previous diseases and injuries.<h4>Methodology/principal findings</h4>We used a cohort that consisted of 48 574 men and 5 409 women who participated in the 90 km ski race Vasaloppet at least once between 1989 and 1998. Number of performed races and finishing time were used as estimates of exercise level. By matching to the National Patient Register we identified participants with severe osteoarthritis, defined as arthroplasty of knee or hip due to osteoarthritis. With an average follow-up of 10 years, we identified 528 men and 42 women with incident osteoarthritis. The crude rate was 1.1/1000 person-years for men and 0.8/1000 person-years for women. Compared with racing once, participation in ≥ 5 races was associated with a 70% higher rate of osteoarthritis (multivariable-adjusted hazard ratio (HR) 1.72, 95% confidence interval (CI) 1.33 to 2.22). The association was dose-dependent with an adjusted HR of 1.09, 95% CI 1.05 to 1.13 for each completed race. A faster finishing time, in comparison with a slow finishing time, was also associated with an increased rate (adjusted HR 1.51, 95% CI 1.14 to 2.01). Contrasting those with 5 or more ski races and a fast finish time to those who only participated once with a slow finish time, the adjusted HR of osteoarthritis was 2.73, 95% CI 1.78 to 4.18.<h4>Conclusions/significance</h4>Participants with multiple and fast races have an increased risk of subsequent arthroplasty of knee and hip due to osteoarthritis, suggesting that intensive exercise may increase the risk.Karl MichaëlssonLiisa BybergAnders AhlbomHåkan MelhusBahman Y FarahmandPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 6, Iss 3, p e18339 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Karl Michaëlsson Liisa Byberg Anders Ahlbom Håkan Melhus Bahman Y Farahmand Risk of severe knee and hip osteoarthritis in relation to level of physical exercise: a prospective cohort study of long-distance skiers in Sweden.
description	<h4>Background</h4>To complete long-distance ski races, regular physical exercise is required. This includes not only cross-country skiing but also endurance exercise during the snow-free seasons. The aim of this study was to determine whether the level of physical exercise is associated with future risk of severe osteoarthritis independent of previous diseases and injuries.<h4>Methodology/principal findings</h4>We used a cohort that consisted of 48 574 men and 5 409 women who participated in the 90 km ski race Vasaloppet at least once between 1989 and 1998. Number of performed races and finishing time were used as estimates of exercise level. By matching to the National Patient Register we identified participants with severe osteoarthritis, defined as arthroplasty of knee or hip due to osteoarthritis. With an average follow-up of 10 years, we identified 528 men and 42 women with incident osteoarthritis. The crude rate was 1.1/1000 person-years for men and 0.8/1000 person-years for women. Compared with racing once, participation in ≥ 5 races was associated with a 70% higher rate of osteoarthritis (multivariable-adjusted hazard ratio (HR) 1.72, 95% confidence interval (CI) 1.33 to 2.22). The association was dose-dependent with an adjusted HR of 1.09, 95% CI 1.05 to 1.13 for each completed race. A faster finishing time, in comparison with a slow finishing time, was also associated with an increased rate (adjusted HR 1.51, 95% CI 1.14 to 2.01). Contrasting those with 5 or more ski races and a fast finish time to those who only participated once with a slow finish time, the adjusted HR of osteoarthritis was 2.73, 95% CI 1.78 to 4.18.<h4>Conclusions/significance</h4>Participants with multiple and fast races have an increased risk of subsequent arthroplasty of knee and hip due to osteoarthritis, suggesting that intensive exercise may increase the risk.
format	article
author	Karl Michaëlsson Liisa Byberg Anders Ahlbom Håkan Melhus Bahman Y Farahmand
author_facet	Karl Michaëlsson Liisa Byberg Anders Ahlbom Håkan Melhus Bahman Y Farahmand
author_sort	Karl Michaëlsson
title	Risk of severe knee and hip osteoarthritis in relation to level of physical exercise: a prospective cohort study of long-distance skiers in Sweden.
title_short	Risk of severe knee and hip osteoarthritis in relation to level of physical exercise: a prospective cohort study of long-distance skiers in Sweden.
title_full	Risk of severe knee and hip osteoarthritis in relation to level of physical exercise: a prospective cohort study of long-distance skiers in Sweden.
title_fullStr	Risk of severe knee and hip osteoarthritis in relation to level of physical exercise: a prospective cohort study of long-distance skiers in Sweden.
title_full_unstemmed	Risk of severe knee and hip osteoarthritis in relation to level of physical exercise: a prospective cohort study of long-distance skiers in Sweden.
title_sort	risk of severe knee and hip osteoarthritis in relation to level of physical exercise: a prospective cohort study of long-distance skiers in sweden.
publisher	Public Library of Science (PLoS)
publishDate	2011
url	https://doaj.org/article/a4719a59ba064531a6dd781f78a2fc0b
work_keys_str_mv	AT karlmichaelsson riskofseverekneeandhiposteoarthritisinrelationtolevelofphysicalexerciseaprospectivecohortstudyoflongdistanceskiersinsweden AT liisabyberg riskofseverekneeandhiposteoarthritisinrelationtolevelofphysicalexerciseaprospectivecohortstudyoflongdistanceskiersinsweden AT andersahlbom riskofseverekneeandhiposteoarthritisinrelationtolevelofphysicalexerciseaprospectivecohortstudyoflongdistanceskiersinsweden AT hakanmelhus riskofseverekneeandhiposteoarthritisinrelationtolevelofphysicalexerciseaprospectivecohortstudyoflongdistanceskiersinsweden AT bahmanyfarahmand riskofseverekneeandhiposteoarthritisinrelationtolevelofphysicalexerciseaprospectivecohortstudyoflongdistanceskiersinsweden
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Risk of severe knee and hip osteoarthritis in relation to level of physical exercise: a prospective cohort study of long-distance skiers in Sweden.

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