Membrane bound monomer of Staphylococcal alpha-hemolysin induces caspase activation and apoptotic cell death despite initiation of membrane repair pathway.
<h4>Background</h4>Wild type Staphylococcal alpha-hemolysin (alpha-HL) assembly on target mammalian cells usually results in necrotic form of cell death; however, caspase activation also occurs. The pathways of caspase activation due to binding/partial assembly by alpha-HL are unknown ti...
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Auteurs principaux: | Saumya S Srivastava, Satyabrata Pany, Amita Sneh, Neesar Ahmed, Aejazur Rahman, Krishnasastry V Musti |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2009
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Accès en ligne: | https://doaj.org/article/a47a6a8880ae4da0be153eea14ba6d5e |
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