Somatosensory lateral inhibition processes modulate motor response inhibition - an EEG source localization study

Abstract Motor inhibitory control is a central executive function, but only recently the importance of perceptual mechanisms for these processes has been focused. It is elusive whether basic mechanisms governing sensory perception affect motor inhibitory control. We examine whether sensory lateral i...

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Autores principales:	Julia Friedrich, Moritz Mückschel, Christian Beste
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a47f3691349b4387bead39e969d51f40
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spelling	oai:doaj.org-article:a47f3691349b4387bead39e969d51f402021-12-02T12:32:05ZSomatosensory lateral inhibition processes modulate motor response inhibition - an EEG source localization study10.1038/s41598-017-04887-z2045-2322https://doaj.org/article/a47f3691349b4387bead39e969d51f402017-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-04887-zhttps://doaj.org/toc/2045-2322Abstract Motor inhibitory control is a central executive function, but only recently the importance of perceptual mechanisms for these processes has been focused. It is elusive whether basic mechanisms governing sensory perception affect motor inhibitory control. We examine whether sensory lateral inhibition (LI) processes modulate motor inhibitory control using a system neurophysiological approach combining EEG signal decomposition with source localization methods in a somatosensory GO/NOGO task. The results show that inter-individual variations in the strength of LI effects predominantly affect processes when information needs to be integrated between cerebral hemispheres. If information needs to be integrated between hemispheres, strong sensory suppression will lead to more impulsive errors. Importantly, the neurophysiological data suggest that not purely perceptual or motor processes are affected. Rather, LI affects the response selection level and modulates processes of stimulus categorization. This is associated with activity modulations in the posterior parietal cortex. The results suggest that when sensory suppression is high and when information needs to be integrated across hemispheres, these processes are less efficient, which likely leads to worse motor inhibitory control. The results show how basis principles modulating perceptual processes affect subsequent motor inhibitory control processes.Julia FriedrichMoritz MückschelChristian BesteNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Julia Friedrich Moritz Mückschel Christian Beste Somatosensory lateral inhibition processes modulate motor response inhibition - an EEG source localization study
description	Abstract Motor inhibitory control is a central executive function, but only recently the importance of perceptual mechanisms for these processes has been focused. It is elusive whether basic mechanisms governing sensory perception affect motor inhibitory control. We examine whether sensory lateral inhibition (LI) processes modulate motor inhibitory control using a system neurophysiological approach combining EEG signal decomposition with source localization methods in a somatosensory GO/NOGO task. The results show that inter-individual variations in the strength of LI effects predominantly affect processes when information needs to be integrated between cerebral hemispheres. If information needs to be integrated between hemispheres, strong sensory suppression will lead to more impulsive errors. Importantly, the neurophysiological data suggest that not purely perceptual or motor processes are affected. Rather, LI affects the response selection level and modulates processes of stimulus categorization. This is associated with activity modulations in the posterior parietal cortex. The results suggest that when sensory suppression is high and when information needs to be integrated across hemispheres, these processes are less efficient, which likely leads to worse motor inhibitory control. The results show how basis principles modulating perceptual processes affect subsequent motor inhibitory control processes.
format	article
author	Julia Friedrich Moritz Mückschel Christian Beste
author_facet	Julia Friedrich Moritz Mückschel Christian Beste
author_sort	Julia Friedrich
title	Somatosensory lateral inhibition processes modulate motor response inhibition - an EEG source localization study
title_short	Somatosensory lateral inhibition processes modulate motor response inhibition - an EEG source localization study
title_full	Somatosensory lateral inhibition processes modulate motor response inhibition - an EEG source localization study
title_fullStr	Somatosensory lateral inhibition processes modulate motor response inhibition - an EEG source localization study
title_full_unstemmed	Somatosensory lateral inhibition processes modulate motor response inhibition - an EEG source localization study
title_sort	somatosensory lateral inhibition processes modulate motor response inhibition - an eeg source localization study
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/a47f3691349b4387bead39e969d51f40
work_keys_str_mv	AT juliafriedrich somatosensorylateralinhibitionprocessesmodulatemotorresponseinhibitionaneegsourcelocalizationstudy AT moritzmuckschel somatosensorylateralinhibitionprocessesmodulatemotorresponseinhibitionaneegsourcelocalizationstudy AT christianbeste somatosensorylateralinhibitionprocessesmodulatemotorresponseinhibitionaneegsourcelocalizationstudy
_version_	1718394176340492288

Somatosensory lateral inhibition processes modulate motor response inhibition - an EEG source localization study

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