A reaction mode of carbene-catalysed aryl aldehyde activation and induced phenol OH functionalization

Selective functionalization of aromatic compounds is important in synthetic chemistry. Here the authors report anN-heterocyclic carbene-catalysed approach for enantioselectively converting ortho-hydroxyaldehydes to cyclic products, via activation of both phenol and aldehyde groups.

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Autores principales:	Xingkuan Chen, Hongling Wang, Kazuki Doitomi, Chong Yih Ooi, Pengcheng Zheng, Wangsheng Liu, Hao Guo, Song Yang, Bao-An Song, Hajime Hirao, Yonggui Robin Chi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a484a29484e34002a823d4811ebf5d65
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spelling	oai:doaj.org-article:a484a29484e34002a823d4811ebf5d652021-12-02T17:01:25ZA reaction mode of carbene-catalysed aryl aldehyde activation and induced phenol OH functionalization10.1038/ncomms155982041-1723https://doaj.org/article/a484a29484e34002a823d4811ebf5d652017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15598https://doaj.org/toc/2041-1723Selective functionalization of aromatic compounds is important in synthetic chemistry. Here the authors report anN-heterocyclic carbene-catalysed approach for enantioselectively converting ortho-hydroxyaldehydes to cyclic products, via activation of both phenol and aldehyde groups.Xingkuan ChenHongling WangKazuki DoitomiChong Yih OoiPengcheng ZhengWangsheng LiuHao GuoSong YangBao-An SongHajime HiraoYonggui Robin ChiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xingkuan Chen Hongling Wang Kazuki Doitomi Chong Yih Ooi Pengcheng Zheng Wangsheng Liu Hao Guo Song Yang Bao-An Song Hajime Hirao Yonggui Robin Chi A reaction mode of carbene-catalysed aryl aldehyde activation and induced phenol OH functionalization
description	Selective functionalization of aromatic compounds is important in synthetic chemistry. Here the authors report anN-heterocyclic carbene-catalysed approach for enantioselectively converting ortho-hydroxyaldehydes to cyclic products, via activation of both phenol and aldehyde groups.
format	article
author	Xingkuan Chen Hongling Wang Kazuki Doitomi Chong Yih Ooi Pengcheng Zheng Wangsheng Liu Hao Guo Song Yang Bao-An Song Hajime Hirao Yonggui Robin Chi
author_facet	Xingkuan Chen Hongling Wang Kazuki Doitomi Chong Yih Ooi Pengcheng Zheng Wangsheng Liu Hao Guo Song Yang Bao-An Song Hajime Hirao Yonggui Robin Chi
author_sort	Xingkuan Chen
title	A reaction mode of carbene-catalysed aryl aldehyde activation and induced phenol OH functionalization
title_short	A reaction mode of carbene-catalysed aryl aldehyde activation and induced phenol OH functionalization
title_full	A reaction mode of carbene-catalysed aryl aldehyde activation and induced phenol OH functionalization
title_fullStr	A reaction mode of carbene-catalysed aryl aldehyde activation and induced phenol OH functionalization
title_full_unstemmed	A reaction mode of carbene-catalysed aryl aldehyde activation and induced phenol OH functionalization
title_sort	reaction mode of carbene-catalysed aryl aldehyde activation and induced phenol oh functionalization
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/a484a29484e34002a823d4811ebf5d65
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A reaction mode of carbene-catalysed aryl aldehyde activation and induced phenol OH functionalization

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