A reaction mode of carbene-catalysed aryl aldehyde activation and induced phenol OH functionalization

Selective functionalization of aromatic compounds is important in synthetic chemistry. Here the authors report anN-heterocyclic carbene-catalysed approach for enantioselectively converting ortho-hydroxyaldehydes to cyclic products, via activation of both phenol and aldehyde groups.

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Autores principales: Xingkuan Chen, Hongling Wang, Kazuki Doitomi, Chong Yih Ooi, Pengcheng Zheng, Wangsheng Liu, Hao Guo, Song Yang, Bao-An Song, Hajime Hirao, Yonggui Robin Chi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/a484a29484e34002a823d4811ebf5d65
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