MapToCleave: High-throughput profiling of microRNA biogenesis in living cells

Summary: Previous large-scale studies have uncovered many features that determine the processing of microRNA (miRNA) precursors; however, they have been conducted in vitro. Here, we introduce MapToCleave, a method to simultaneously profile processing of thousands of distinct RNA structures in living...

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Bibliographic Details
Main Authors: Wenjing Kang, Bastian Fromm, Anna J. Houben, Eirik Høye, Daniela Bezdan, Carme Arnan, Kim Thrane, Michaela Asp, Rory Johnson, Inna Biryukova, Marc R. Friedländer
Format: article
Language:EN
Published: Elsevier 2021
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Online Access:https://doaj.org/article/a48756e75c7e4b9698433294be9c47f4
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