Therapeutic targeting using tumor specific peptides inhibits long non-coding RNA HOTAIR activity in ovarian and breast cancer

Therapeutic targeting using tumor specific peptides inhibits long non-coding RNA HOTAIR activity in ovarian and breast cancer

Abstract Long non-coding RNAs (lncRNAs) play key roles in human diseases, including cancer. Functional studies of the lncRNA HOTAIR (HOX transcript antisense RNA) provide compelling evidence for therapeutic targeting of HOTAIR in cancer, but targeting lncRNAs in vivo has proven to be difficult. In t...

Full description

Saved in:
Bibliographic Details
Main Authors: Ali R. Özeş, Yinu Wang, Xingyue Zong, Fang Fang, Jay Pilrose, Kenneth P. Nephew
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/a4984e39a24a4c25bbce174adce2e7db
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items