ALDH1 expression predicts progression of premalignant lesions to cancer in Type I endometrial carcinomas

ALDH1 expression predicts progression of premalignant lesions to cancer in Type I endometrial carcinomas

Abstract In type 1 endometrial cancer, unopposed estrogen stimulation is thought to lead to endometrial hyperplasia which precedes malignant progression. Recent data from our group and others suggest that ALDH activity mediates stemness in endometrial cancer, but while aldehyde dehydrogenase 1 (ALDH...

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Autores principales: Vei Mah, Yahya Elshimali, Alison Chu, Neda A. Moatamed, Jamar P. Uzzell, Jessica Tsui, Stephen Schettler, Hania Shakeri, Madhuri Wadehra
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a4999bcdf8744e5fbea3ffe78e4fe2a3
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