Effect of Eight-Month Exercise Intervention on Bone Outcomes of Young Opioid-Dependent Women

Objective: To evaluate the bone response to an 8 month aerobic gymnastics training program in young opioid-addicted women. Design: Randomized controlled trial (parallel design). Setting: Women’s Specific Drug Rehabilitation Center in China. Patients: One hundred and two young women with low bone qua...

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Autores principales:	Zenghui Ding, Zuchang Ma, Xianjun Yang, Yining Sun
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	drug abuse exercise intervention bone quality body composition Medicine R
Acceso en línea:	https://doaj.org/article/a49a2e5351714982a372c44df0b3f245
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spelling	oai:doaj.org-article:a49a2e5351714982a372c44df0b3f2452021-11-11T16:28:22ZEffect of Eight-Month Exercise Intervention on Bone Outcomes of Young Opioid-Dependent Women10.3390/ijerph1821113361660-46011661-7827https://doaj.org/article/a49a2e5351714982a372c44df0b3f2452021-10-01T00:00:00Zhttps://www.mdpi.com/1660-4601/18/21/11336https://doaj.org/toc/1661-7827https://doaj.org/toc/1660-4601Objective: To evaluate the bone response to an 8 month aerobic gymnastics training program in young opioid-addicted women. Design: Randomized controlled trial (parallel design). Setting: Women’s Specific Drug Rehabilitation Center in China. Patients: One hundred and two young women with low bone quality and previous opioid addiction were divided into two groups: (a) the low bone quality intervention experimental group (n = 55; age: 30.3 ± 6.1) and (b) the low bone quality observed control group (observation group; n = 47; age: 29.0 ± 5.3). Interventions: The intervention group took aerobic gymnastics regularly for 80 min/d and 5 d/wk for 8 months and completed follow-up testing. Main Outcome Measures: Substance use history and other life habits affecting bone quality were assessed by questionnaire-based interviews. Bone quality (stiffness-index, T-score, Z-score) was examined with quantitative ultrasound. Anthropometric characteristics (body weight, fat-free mass, fat mass) were obtained by bioelectrical impedance analysis. Results: After the 8 month intervention, the stiffness index of bone quality increased significantly (before: 82 ± 6, after: 108 ± 14, <i>p</i> < 0.05) in the experimental group. However, the bone quality did not change significantly in the controls (before: 79 ± 10, after: 77 ± 13, <i>p</i> > 0.05). The bone change in the difference group was significant (experimental group: 31.7% vs observation group: -0.03%). Fat mass decreased in the experimental group (experimental group: before: 19.6 ± 3.7 kg, after: 18.8 ± 4.0 kg, <i>p</i> < 0.05). Meanwhile, the change in fat-free mass was the determination of the change in bone quality in the experimental group. Conclusions: Our results suggested that aerobic gymnastics intervention can be an effective strategy for the prevention and treatment of drug-induced osteoporosis in detoxification addicts.Zenghui DingZuchang MaXianjun YangYining SunMDPI AGarticledrug abuseexercise interventionbone qualitybody compositionMedicineRENInternational Journal of Environmental Research and Public Health, Vol 18, Iss 11336, p 11336 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	drug abuse exercise intervention bone quality body composition Medicine R
spellingShingle	drug abuse exercise intervention bone quality body composition Medicine R Zenghui Ding Zuchang Ma Xianjun Yang Yining Sun Effect of Eight-Month Exercise Intervention on Bone Outcomes of Young Opioid-Dependent Women
description	Objective: To evaluate the bone response to an 8 month aerobic gymnastics training program in young opioid-addicted women. Design: Randomized controlled trial (parallel design). Setting: Women’s Specific Drug Rehabilitation Center in China. Patients: One hundred and two young women with low bone quality and previous opioid addiction were divided into two groups: (a) the low bone quality intervention experimental group (n = 55; age: 30.3 ± 6.1) and (b) the low bone quality observed control group (observation group; n = 47; age: 29.0 ± 5.3). Interventions: The intervention group took aerobic gymnastics regularly for 80 min/d and 5 d/wk for 8 months and completed follow-up testing. Main Outcome Measures: Substance use history and other life habits affecting bone quality were assessed by questionnaire-based interviews. Bone quality (stiffness-index, T-score, Z-score) was examined with quantitative ultrasound. Anthropometric characteristics (body weight, fat-free mass, fat mass) were obtained by bioelectrical impedance analysis. Results: After the 8 month intervention, the stiffness index of bone quality increased significantly (before: 82 ± 6, after: 108 ± 14, <i>p</i> < 0.05) in the experimental group. However, the bone quality did not change significantly in the controls (before: 79 ± 10, after: 77 ± 13, <i>p</i> > 0.05). The bone change in the difference group was significant (experimental group: 31.7% vs observation group: -0.03%). Fat mass decreased in the experimental group (experimental group: before: 19.6 ± 3.7 kg, after: 18.8 ± 4.0 kg, <i>p</i> < 0.05). Meanwhile, the change in fat-free mass was the determination of the change in bone quality in the experimental group. Conclusions: Our results suggested that aerobic gymnastics intervention can be an effective strategy for the prevention and treatment of drug-induced osteoporosis in detoxification addicts.
format	article
author	Zenghui Ding Zuchang Ma Xianjun Yang Yining Sun
author_facet	Zenghui Ding Zuchang Ma Xianjun Yang Yining Sun
author_sort	Zenghui Ding
title	Effect of Eight-Month Exercise Intervention on Bone Outcomes of Young Opioid-Dependent Women
title_short	Effect of Eight-Month Exercise Intervention on Bone Outcomes of Young Opioid-Dependent Women
title_full	Effect of Eight-Month Exercise Intervention on Bone Outcomes of Young Opioid-Dependent Women
title_fullStr	Effect of Eight-Month Exercise Intervention on Bone Outcomes of Young Opioid-Dependent Women
title_full_unstemmed	Effect of Eight-Month Exercise Intervention on Bone Outcomes of Young Opioid-Dependent Women
title_sort	effect of eight-month exercise intervention on bone outcomes of young opioid-dependent women
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/a49a2e5351714982a372c44df0b3f245
work_keys_str_mv	AT zenghuiding effectofeightmonthexerciseinterventiononboneoutcomesofyoungopioiddependentwomen AT zuchangma effectofeightmonthexerciseinterventiononboneoutcomesofyoungopioiddependentwomen AT xianjunyang effectofeightmonthexerciseinterventiononboneoutcomesofyoungopioiddependentwomen AT yiningsun effectofeightmonthexerciseinterventiononboneoutcomesofyoungopioiddependentwomen
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Effect of Eight-Month Exercise Intervention on Bone Outcomes of Young Opioid-Dependent Women

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