Mechanisms of Attenuation by Genetic Recoding of Viruses

The development of safe and effective vaccines against viruses is central to disease control. With advancements in DNA synthesis technology, the production of synthetic viral genomes has fueled many research efforts that aim to generate attenuated viruses by introducing synonymous mutations.

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Autores principales: Daniel Gonçalves-Carneiro, Paul D. Bieniasz
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Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/a4a12a16395d4349b9fb36b56d5f33b1
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spelling oai:doaj.org-article:a4a12a16395d4349b9fb36b56d5f33b12021-11-03T18:15:38ZMechanisms of Attenuation by Genetic Recoding of Viruses2161-21292150-751110.1128/mBio.02238-20https://doaj.org/article/a4a12a16395d4349b9fb36b56d5f33b12021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02238-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 The development of safe and effective vaccines against viruses is central to disease control. With advancements in DNA synthesis technology, the production of synthetic viral genomes has fueled many research efforts that aim to generate attenuated viruses by introducing synonymous mutations.Daniel Gonçalves-CarneiroPaul D. BieniaszAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Daniel Gonçalves-Carneiro
Paul D. Bieniasz
Mechanisms of Attenuation by Genetic Recoding of Viruses
description The development of safe and effective vaccines against viruses is central to disease control. With advancements in DNA synthesis technology, the production of synthetic viral genomes has fueled many research efforts that aim to generate attenuated viruses by introducing synonymous mutations.
format article
author Daniel Gonçalves-Carneiro
Paul D. Bieniasz
author_facet Daniel Gonçalves-Carneiro
Paul D. Bieniasz
author_sort Daniel Gonçalves-Carneiro
title Mechanisms of Attenuation by Genetic Recoding of Viruses
title_short Mechanisms of Attenuation by Genetic Recoding of Viruses
title_full Mechanisms of Attenuation by Genetic Recoding of Viruses
title_fullStr Mechanisms of Attenuation by Genetic Recoding of Viruses
title_full_unstemmed Mechanisms of Attenuation by Genetic Recoding of Viruses
title_sort mechanisms of attenuation by genetic recoding of viruses
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/a4a12a16395d4349b9fb36b56d5f33b1
work_keys_str_mv AT danielgoncalvescarneiro mechanismsofattenuationbygeneticrecodingofviruses
AT pauldbieniasz mechanismsofattenuationbygeneticrecodingofviruses
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