Mechanisms of Attenuation by Genetic Recoding of Viruses
The development of safe and effective vaccines against viruses is central to disease control. With advancements in DNA synthesis technology, the production of synthetic viral genomes has fueled many research efforts that aim to generate attenuated viruses by introducing synonymous mutations.
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American Society for Microbiology
2021
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oai:doaj.org-article:a4a12a16395d4349b9fb36b56d5f33b12021-11-03T18:15:38ZMechanisms of Attenuation by Genetic Recoding of Viruses2161-21292150-751110.1128/mBio.02238-20https://doaj.org/article/a4a12a16395d4349b9fb36b56d5f33b12021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02238-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 The development of safe and effective vaccines against viruses is central to disease control. With advancements in DNA synthesis technology, the production of synthetic viral genomes has fueled many research efforts that aim to generate attenuated viruses by introducing synonymous mutations.Daniel Gonçalves-CarneiroPaul D. BieniaszAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021) |
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DOAJ |
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EN |
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Microbiology QR1-502 |
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Microbiology QR1-502 Daniel Gonçalves-Carneiro Paul D. Bieniasz Mechanisms of Attenuation by Genetic Recoding of Viruses |
description |
The development of safe and effective vaccines against viruses is central to disease control. With advancements in DNA synthesis technology, the production of synthetic viral genomes has fueled many research efforts that aim to generate attenuated viruses by introducing synonymous mutations. |
format |
article |
author |
Daniel Gonçalves-Carneiro Paul D. Bieniasz |
author_facet |
Daniel Gonçalves-Carneiro Paul D. Bieniasz |
author_sort |
Daniel Gonçalves-Carneiro |
title |
Mechanisms of Attenuation by Genetic Recoding of Viruses |
title_short |
Mechanisms of Attenuation by Genetic Recoding of Viruses |
title_full |
Mechanisms of Attenuation by Genetic Recoding of Viruses |
title_fullStr |
Mechanisms of Attenuation by Genetic Recoding of Viruses |
title_full_unstemmed |
Mechanisms of Attenuation by Genetic Recoding of Viruses |
title_sort |
mechanisms of attenuation by genetic recoding of viruses |
publisher |
American Society for Microbiology |
publishDate |
2021 |
url |
https://doaj.org/article/a4a12a16395d4349b9fb36b56d5f33b1 |
work_keys_str_mv |
AT danielgoncalvescarneiro mechanismsofattenuationbygeneticrecodingofviruses AT pauldbieniasz mechanismsofattenuationbygeneticrecodingofviruses |
_version_ |
1718445475373252608 |