Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency.

Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency.

It has been demonstrated for some cancers that the frequency of somatic oncogenic mutations may vary in ancestral populations. To determine whether key driver alterations might occur at different frequencies in colorectal cancer, we applied a high-throughput genotyping platform (OncoMap) to query 38...

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Détails bibliographiques
Auteurs principaux: Megan C Hanna, Christina Go, Christine Roden, Robert T Jones, Panisa Pochanard, Ahmed Yasir Javed, Awais Javed, Chandrani Mondal, Emanuele Palescandolo, Paul Van Hummelen, Charles Hatton, Adam J Bass, Sung Min Chun, Deuk Chae Na, Tae-Im Kim, Se Jin Jang, Raymond U Osarogiagbon, William C Hahn, Matthew Meyerson, Levi A Garraway, Laura E MacConaill
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/a4a1da8169604c15b81e8f98eabbb7dd
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