COVID-19 in Pediatric Inpatients: A Multi-Center Observational Study of Factors Associated with Negative Short-Term Outcomes

Most cases of COVID-19 in children and adolescents are mild or asymptomatic, but a small number of individuals may develop severe disease, requiring PICU admission and/or mechanical ventilation. We assessed the factors associated with negative short-term outcomes of COVID-19 in 82 pediatric patients...

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Autores principales:	Sara Rubenstein, Emily Grew, Katharine Clouser, Alexander Kwok, Aravindhan Veerapandiyan, Jeffrey Kornitzer, Keith Pecor, Xue Ming
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	COVID-19 age body mass index pediatric intensive care unit respiratory support Pediatrics RJ1-570
Acceso en línea:	https://doaj.org/article/a4a2a2f554e441a0a6c1d2300a9ad131
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spelling	oai:doaj.org-article:a4a2a2f554e441a0a6c1d2300a9ad1312021-11-25T17:13:51ZCOVID-19 in Pediatric Inpatients: A Multi-Center Observational Study of Factors Associated with Negative Short-Term Outcomes10.3390/children81109512227-9067https://doaj.org/article/a4a2a2f554e441a0a6c1d2300a9ad1312021-10-01T00:00:00Zhttps://www.mdpi.com/2227-9067/8/11/951https://doaj.org/toc/2227-9067Most cases of COVID-19 in children and adolescents are mild or asymptomatic, but a small number of individuals may develop severe disease, requiring PICU admission and/or mechanical ventilation. We assessed the factors associated with negative short-term outcomes of COVID-19 in 82 pediatric patients at three hospitals within the United States during the spring and summer of 2020 using medical records, laboratory data, and imaging studies of all patients admitted with a positive RT-PCR test for SARS-CoV-2. We found that older patients were more likely to have an extended hospital stay, and those with high BMIs (over 25) were more likely to be admitted to the PICU during the early pandemic. In addition, older patients, those with high BMIs, and those with underlying medical conditions, were more likely to receive respiratory support. Given the association of age, BMI, and underlying medical conditions with more severe COVID-19, clinicians should keep these factors in mind when treating patients.Sara RubensteinEmily GrewKatharine ClouserAlexander KwokAravindhan VeerapandiyanJeffrey KornitzerKeith PecorXue MingMDPI AGarticleCOVID-19agebody mass indexpediatric intensive care unitrespiratory supportPediatricsRJ1-570ENChildren, Vol 8, Iss 951, p 951 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID-19 age body mass index pediatric intensive care unit respiratory support Pediatrics RJ1-570
spellingShingle	COVID-19 age body mass index pediatric intensive care unit respiratory support Pediatrics RJ1-570 Sara Rubenstein Emily Grew Katharine Clouser Alexander Kwok Aravindhan Veerapandiyan Jeffrey Kornitzer Keith Pecor Xue Ming COVID-19 in Pediatric Inpatients: A Multi-Center Observational Study of Factors Associated with Negative Short-Term Outcomes
description	Most cases of COVID-19 in children and adolescents are mild or asymptomatic, but a small number of individuals may develop severe disease, requiring PICU admission and/or mechanical ventilation. We assessed the factors associated with negative short-term outcomes of COVID-19 in 82 pediatric patients at three hospitals within the United States during the spring and summer of 2020 using medical records, laboratory data, and imaging studies of all patients admitted with a positive RT-PCR test for SARS-CoV-2. We found that older patients were more likely to have an extended hospital stay, and those with high BMIs (over 25) were more likely to be admitted to the PICU during the early pandemic. In addition, older patients, those with high BMIs, and those with underlying medical conditions, were more likely to receive respiratory support. Given the association of age, BMI, and underlying medical conditions with more severe COVID-19, clinicians should keep these factors in mind when treating patients.
format	article
author	Sara Rubenstein Emily Grew Katharine Clouser Alexander Kwok Aravindhan Veerapandiyan Jeffrey Kornitzer Keith Pecor Xue Ming
author_facet	Sara Rubenstein Emily Grew Katharine Clouser Alexander Kwok Aravindhan Veerapandiyan Jeffrey Kornitzer Keith Pecor Xue Ming
author_sort	Sara Rubenstein
title	COVID-19 in Pediatric Inpatients: A Multi-Center Observational Study of Factors Associated with Negative Short-Term Outcomes
title_short	COVID-19 in Pediatric Inpatients: A Multi-Center Observational Study of Factors Associated with Negative Short-Term Outcomes
title_full	COVID-19 in Pediatric Inpatients: A Multi-Center Observational Study of Factors Associated with Negative Short-Term Outcomes
title_fullStr	COVID-19 in Pediatric Inpatients: A Multi-Center Observational Study of Factors Associated with Negative Short-Term Outcomes
title_full_unstemmed	COVID-19 in Pediatric Inpatients: A Multi-Center Observational Study of Factors Associated with Negative Short-Term Outcomes
title_sort	covid-19 in pediatric inpatients: a multi-center observational study of factors associated with negative short-term outcomes
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/a4a2a2f554e441a0a6c1d2300a9ad131
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COVID-19 in Pediatric Inpatients: A Multi-Center Observational Study of Factors Associated with Negative Short-Term Outcomes

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