LncRNA HOTAIRM1 promotes MDSC expansion and suppressive functions through the HOXA1-miR124 axis during HCV infection

LncRNA HOTAIRM1 promotes MDSC expansion and suppressive functions through the HOXA1-miR124 axis during HCV infection

Abstract HOXA transcript antisense RNA myeloid-specific 1 (HOTAIRM1) is a long non-coding RNA (lncRNA) that plays a pivotal role in regulating myeloid cell development via targeting HOXA1 gene expression. We and others have previously shown that myeloid-derived suppressor cells (MDSCs), a heterogene...

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Autores principales: Bal Krishna Chand Thakuri, Jinyu Zhang, Juan Zhao, Lam N. Nguyen, Lam N. T. Nguyen, Sushant Khanal, Dechao Cao, Xindi Dang, Madison Schank, Xiao Y. Wu, Zheng D. Morrison, Mohamed El Gazzar, Zhengke Li, Yong Jiang, Shunbin Ning, Ling Wang, Jonathan P. Moorman, Zhi Q. Yao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a4a3ec38509049228aa48ba468be63bc
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