Application of FTIR Spectroscopy and Chemometrics for the Prediction of Radical Scavenging Activities of Fish oils

Patin fish (Pangasius micronemus), Gabus fish (Channa striata) and Bandeng fish (Chanos chanos) are the freshwater fish that are widely cultivated in Indonesia, fish oils extracted are believed has antioxidant activity. The goals of this study was (1) determining antioxidant activities using radical...

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Autores principales:	Arif Nur Ikhsan, Abdul Rohman, Anggita Rosiana Putri, Fella Syifa, Mabrurotul Mustafidah, Ronny Martien
Formato:	article
Lenguaje:	EN
Publicado:	Universitas Gadjah Mada 2021
Materias:	fish oil ftir antioxidant activity chemometrics Pharmacy and materia medica RS1-441
Acceso en línea:	https://doaj.org/article/a4a99483caa94f62982466a88e49ab2b
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spelling	oai:doaj.org-article:a4a99483caa94f62982466a88e49ab2b2021-11-15T06:08:46ZApplication of FTIR Spectroscopy and Chemometrics for the Prediction of Radical Scavenging Activities of Fish oils2338-94272338-948610.22146/ijp.1004https://doaj.org/article/a4a99483caa94f62982466a88e49ab2b2021-06-01T00:00:00Zhttps://jurnal.ugm.ac.id/v3/IJP/article/view/1004https://doaj.org/toc/2338-9427https://doaj.org/toc/2338-9486Patin fish (Pangasius micronemus), Gabus fish (Channa striata) and Bandeng fish (Chanos chanos) are the freshwater fish that are widely cultivated in Indonesia, fish oils extracted are believed has antioxidant activity. The goals of this study was (1) determining antioxidant activities using radical scavenging activity (RSA) 2,2’-diphenyl-1-picrylhydrazil (DPPH), (2) classifying of fish oil from different species and extraction method using principal component analysis (PCA) and cluster analysis (CA) and predicting antioxidant activities of fish oil from different species and extraction method using FTIR spectroscopy combined principal component regression (PCR) and partial least square regression (PLS). The results exhibit radical scavenging activity (RSA) of patin fish flesh oil (maceration dried samples using chloroform) giving highest RSA (23.57 ± 0.14). PCA and CA succesfully classify of fish oil from different species and extraction based on PC1 - PC2 score plots and grouping into 4 groups based on dendogram. Optimal PCR method were obtained from second derivative spectra at wavenumbers region 1440 – 1741 cm-1 with highest R2 (0,9794), lowest RMSEC (0,737), and lowest RMSEP (0,927) in calibration and validation models. From this study we can concluded FTIR spectroscopy combined with chemometrics can be classifying and predicting antioxidant activity of fish oil from different species and extraction method successfully.Arif Nur IkhsanAbdul RohmanAnggita Rosiana PutriFella SyifaMabrurotul MustafidahRonny MartienUniversitas Gadjah Madaarticlefish oilftirantioxidant activitychemometricsPharmacy and materia medicaRS1-441ENIndonesian Journal of Pharmacy, Pp 166-174 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	fish oil ftir antioxidant activity chemometrics Pharmacy and materia medica RS1-441
spellingShingle	fish oil ftir antioxidant activity chemometrics Pharmacy and materia medica RS1-441 Arif Nur Ikhsan Abdul Rohman Anggita Rosiana Putri Fella Syifa Mabrurotul Mustafidah Ronny Martien Application of FTIR Spectroscopy and Chemometrics for the Prediction of Radical Scavenging Activities of Fish oils
description	Patin fish (Pangasius micronemus), Gabus fish (Channa striata) and Bandeng fish (Chanos chanos) are the freshwater fish that are widely cultivated in Indonesia, fish oils extracted are believed has antioxidant activity. The goals of this study was (1) determining antioxidant activities using radical scavenging activity (RSA) 2,2’-diphenyl-1-picrylhydrazil (DPPH), (2) classifying of fish oil from different species and extraction method using principal component analysis (PCA) and cluster analysis (CA) and predicting antioxidant activities of fish oil from different species and extraction method using FTIR spectroscopy combined principal component regression (PCR) and partial least square regression (PLS). The results exhibit radical scavenging activity (RSA) of patin fish flesh oil (maceration dried samples using chloroform) giving highest RSA (23.57 ± 0.14). PCA and CA succesfully classify of fish oil from different species and extraction based on PC1 - PC2 score plots and grouping into 4 groups based on dendogram. Optimal PCR method were obtained from second derivative spectra at wavenumbers region 1440 – 1741 cm-1 with highest R2 (0,9794), lowest RMSEC (0,737), and lowest RMSEP (0,927) in calibration and validation models. From this study we can concluded FTIR spectroscopy combined with chemometrics can be classifying and predicting antioxidant activity of fish oil from different species and extraction method successfully.
format	article
author	Arif Nur Ikhsan Abdul Rohman Anggita Rosiana Putri Fella Syifa Mabrurotul Mustafidah Ronny Martien
author_facet	Arif Nur Ikhsan Abdul Rohman Anggita Rosiana Putri Fella Syifa Mabrurotul Mustafidah Ronny Martien
author_sort	Arif Nur Ikhsan
title	Application of FTIR Spectroscopy and Chemometrics for the Prediction of Radical Scavenging Activities of Fish oils
title_short	Application of FTIR Spectroscopy and Chemometrics for the Prediction of Radical Scavenging Activities of Fish oils
title_full	Application of FTIR Spectroscopy and Chemometrics for the Prediction of Radical Scavenging Activities of Fish oils
title_fullStr	Application of FTIR Spectroscopy and Chemometrics for the Prediction of Radical Scavenging Activities of Fish oils
title_full_unstemmed	Application of FTIR Spectroscopy and Chemometrics for the Prediction of Radical Scavenging Activities of Fish oils
title_sort	application of ftir spectroscopy and chemometrics for the prediction of radical scavenging activities of fish oils
publisher	Universitas Gadjah Mada
publishDate	2021
url	https://doaj.org/article/a4a99483caa94f62982466a88e49ab2b
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Application of FTIR Spectroscopy and Chemometrics for the Prediction of Radical Scavenging Activities of Fish oils

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