Forward design of a complex enzyme cascade reaction
Building multi-component enzymatic processes in one pot is challenged by the inherent complexity of each biochemical system. Here, the authors use online mass spectroscopy and engineering systems theory to achieve forward design of a ten-membered reaction cascade.
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Nature Portfolio
2016
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oai:doaj.org-article:a4ae650a8587454da4b1d55a81d31cda2021-12-02T17:32:05ZForward design of a complex enzyme cascade reaction10.1038/ncomms129712041-1723https://doaj.org/article/a4ae650a8587454da4b1d55a81d31cda2016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12971https://doaj.org/toc/2041-1723Building multi-component enzymatic processes in one pot is challenged by the inherent complexity of each biochemical system. Here, the authors use online mass spectroscopy and engineering systems theory to achieve forward design of a ten-membered reaction cascade.Christoph HoldSonja BillerbeckSven PankeNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016) |
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DOAJ |
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EN |
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Science Q |
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Science Q Christoph Hold Sonja Billerbeck Sven Panke Forward design of a complex enzyme cascade reaction |
description |
Building multi-component enzymatic processes in one pot is challenged by the inherent complexity of each biochemical system. Here, the authors use online mass spectroscopy and engineering systems theory to achieve forward design of a ten-membered reaction cascade. |
format |
article |
author |
Christoph Hold Sonja Billerbeck Sven Panke |
author_facet |
Christoph Hold Sonja Billerbeck Sven Panke |
author_sort |
Christoph Hold |
title |
Forward design of a complex enzyme cascade reaction |
title_short |
Forward design of a complex enzyme cascade reaction |
title_full |
Forward design of a complex enzyme cascade reaction |
title_fullStr |
Forward design of a complex enzyme cascade reaction |
title_full_unstemmed |
Forward design of a complex enzyme cascade reaction |
title_sort |
forward design of a complex enzyme cascade reaction |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/a4ae650a8587454da4b1d55a81d31cda |
work_keys_str_mv |
AT christophhold forwarddesignofacomplexenzymecascadereaction AT sonjabillerbeck forwarddesignofacomplexenzymecascadereaction AT svenpanke forwarddesignofacomplexenzymecascadereaction |
_version_ |
1718380387533586432 |