Pharmacological targeting of Sam68 functions in colorectal cancer stem cells

Pharmacological targeting of Sam68 functions in colorectal cancer stem cells

Summary: Cancer stem cells (CSCs) are documented to play a key role in tumorigenesis and therapy resistance. Despite significant progress in clinical oncology, CSC reservoirs remain elusive and difficult to eliminate. Reverse-turn peptidomimetics were characterized as disruptors of CBP/beta-Catenin...

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Autores principales: Angelique N. Masibag, Christopher J. Bergin, Joshua R. Haebe, Aïcha Zouggar, Muhammad S. Shah, Tamara Sandouka, Amanda Mendes da Silva, François M. Desrochers, Aube Fournier-Morin, Yannick D. Benoit
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Pharmacology
Biochemistry
Stem cells research
Cancer
Science
Q
Acceso en línea:https://doaj.org/article/a4b364fa1b8740e1b8dceb3a7778dcb2
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