NAC blocks Cystatin C amyloid complex aggregation in a cell system and in skin of HCCAA patients
HCCAA is a dominantly inherited disease which causes brain hemorrhages as a result of mutant cystatin C aggregation in carriers. Here, the authors show that n- acetyl cysteine can prevent aggregation of mutant protein in a cell model system and reverse protein deposition in the skin of mutation-carr...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2021
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/a4b751bc357945ceb32e93795210aa97 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|