Human induced pluripotent stem cell-based platform for modeling cardiac ischemia

Abstract Ischemic heart disease is a major cause of death worldwide, and the only available therapy to salvage the tissue is reperfusion, which can initially cause further damage. Many therapeutics that have been promising in animal models have failed in human trials. Thus, functional human based ca...

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Autores principales: Martta Häkli, Joose Kreutzer, Antti-Juhana Mäki, Hannu Välimäki, Henna Lappi, Heini Huhtala, Pasi Kallio, Katriina Aalto-Setälä, Mari Pekkanen-Mattila
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a4b8f6361442485f8e2228b64c1c0b3a
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