Statistical modeling of RNA structure profiling experiments enables parsimonious reconstruction of structure landscapes

Different experimental and computational approaches can be used to study RNA structures. Here, the authors present a computational method for data-directed reconstruction of complex RNA structure landscapes, which predicts a parsimonious set of co-existing structures and estimates their abundances f...

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Detalles Bibliográficos
Autores principales:	Hua Li, Sharon Aviran
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a4ce7826408646cbb8880ad8331024ff
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spelling	oai:doaj.org-article:a4ce7826408646cbb8880ad8331024ff2021-12-02T14:39:23ZStatistical modeling of RNA structure profiling experiments enables parsimonious reconstruction of structure landscapes10.1038/s41467-018-02923-82041-1723https://doaj.org/article/a4ce7826408646cbb8880ad8331024ff2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02923-8https://doaj.org/toc/2041-1723Different experimental and computational approaches can be used to study RNA structures. Here, the authors present a computational method for data-directed reconstruction of complex RNA structure landscapes, which predicts a parsimonious set of co-existing structures and estimates their abundances from structure profiling data.Hua LiSharon AviranNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hua Li Sharon Aviran Statistical modeling of RNA structure profiling experiments enables parsimonious reconstruction of structure landscapes
description	Different experimental and computational approaches can be used to study RNA structures. Here, the authors present a computational method for data-directed reconstruction of complex RNA structure landscapes, which predicts a parsimonious set of co-existing structures and estimates their abundances from structure profiling data.
format	article
author	Hua Li Sharon Aviran
author_facet	Hua Li Sharon Aviran
author_sort	Hua Li
title	Statistical modeling of RNA structure profiling experiments enables parsimonious reconstruction of structure landscapes
title_short	Statistical modeling of RNA structure profiling experiments enables parsimonious reconstruction of structure landscapes
title_full	Statistical modeling of RNA structure profiling experiments enables parsimonious reconstruction of structure landscapes
title_fullStr	Statistical modeling of RNA structure profiling experiments enables parsimonious reconstruction of structure landscapes
title_full_unstemmed	Statistical modeling of RNA structure profiling experiments enables parsimonious reconstruction of structure landscapes
title_sort	statistical modeling of rna structure profiling experiments enables parsimonious reconstruction of structure landscapes
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/a4ce7826408646cbb8880ad8331024ff
work_keys_str_mv	AT huali statisticalmodelingofrnastructureprofilingexperimentsenablesparsimoniousreconstructionofstructurelandscapes AT sharonaviran statisticalmodelingofrnastructureprofilingexperimentsenablesparsimoniousreconstructionofstructurelandscapes
_version_	1718390673284005888

Statistical modeling of RNA structure profiling experiments enables parsimonious reconstruction of structure landscapes

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