The structural dynamics of macropinosome formation and PI3-kinase-mediated sealing revealed by lattice light sheet microscopy
Macropinocytosis is a cellular process for the uptake of extracellular fluid. Here, the authors use lattice light sheet microscopy to examine the spatial dynamics of the plasma membrane, PI3K activity, and structural differences of various macrophage cell types during macropinocytosis.
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Nature Portfolio
2021
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oai:doaj.org-article:a4d0a54149e7410e8dfc5feb28705c332021-12-02T15:08:40ZThe structural dynamics of macropinosome formation and PI3-kinase-mediated sealing revealed by lattice light sheet microscopy10.1038/s41467-021-25187-12041-1723https://doaj.org/article/a4d0a54149e7410e8dfc5feb28705c332021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25187-1https://doaj.org/toc/2041-1723Macropinocytosis is a cellular process for the uptake of extracellular fluid. Here, the authors use lattice light sheet microscopy to examine the spatial dynamics of the plasma membrane, PI3K activity, and structural differences of various macrophage cell types during macropinocytosis.Shayne E. QuinnLu HuangJason G. KerkvlietJoel A. SwansonSteve SmithAdam D. HoppeRobert B. AndersonNatalie W. ThiexBrandon L. ScottNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
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EN |
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Science Q |
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Science Q Shayne E. Quinn Lu Huang Jason G. Kerkvliet Joel A. Swanson Steve Smith Adam D. Hoppe Robert B. Anderson Natalie W. Thiex Brandon L. Scott The structural dynamics of macropinosome formation and PI3-kinase-mediated sealing revealed by lattice light sheet microscopy |
| description |
Macropinocytosis is a cellular process for the uptake of extracellular fluid. Here, the authors use lattice light sheet microscopy to examine the spatial dynamics of the plasma membrane, PI3K activity, and structural differences of various macrophage cell types during macropinocytosis. |
| format |
article |
| author |
Shayne E. Quinn Lu Huang Jason G. Kerkvliet Joel A. Swanson Steve Smith Adam D. Hoppe Robert B. Anderson Natalie W. Thiex Brandon L. Scott |
| author_facet |
Shayne E. Quinn Lu Huang Jason G. Kerkvliet Joel A. Swanson Steve Smith Adam D. Hoppe Robert B. Anderson Natalie W. Thiex Brandon L. Scott |
| author_sort |
Shayne E. Quinn |
| title |
The structural dynamics of macropinosome formation and PI3-kinase-mediated sealing revealed by lattice light sheet microscopy |
| title_short |
The structural dynamics of macropinosome formation and PI3-kinase-mediated sealing revealed by lattice light sheet microscopy |
| title_full |
The structural dynamics of macropinosome formation and PI3-kinase-mediated sealing revealed by lattice light sheet microscopy |
| title_fullStr |
The structural dynamics of macropinosome formation and PI3-kinase-mediated sealing revealed by lattice light sheet microscopy |
| title_full_unstemmed |
The structural dynamics of macropinosome formation and PI3-kinase-mediated sealing revealed by lattice light sheet microscopy |
| title_sort |
structural dynamics of macropinosome formation and pi3-kinase-mediated sealing revealed by lattice light sheet microscopy |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/a4d0a54149e7410e8dfc5feb28705c33 |
| work_keys_str_mv |
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