Loss of central auditory processing in a mouse model of Canavan disease.
Canavan Disease (CD) is a leukodystrophy caused by homozygous null mutations in the gene encoding aspartoacylase (ASPA). ASPA-deficiency is characterized by severe psychomotor retardation, and excessive levels of the ASPA substrate N-acetylaspartate (NAA). ASPA is an oligodendrocyte marker and it is...
Guardado en:
Autores principales: | Georg von Jonquieres, Kristina E Froud, Claudia B Klugmann, Ann C Y Wong, Gary D Housley, Matthias Klugmann |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/a4defe9bf1c8429dae4aabbe4823e2b9 |
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