Burden of Healthcare-Associated Infections in Sicily, Italy: Estimates from the Regional Point Prevalence Surveys 2016–2018

An assessment of the burden of healthcare-associated infections (HAIs) in terms of disability-adjusted life years (DALYs) is useful for comparing and ranking HAIs and to support infection prevention and control strategies. We estimated the burden of healthcare-associated pneumoniae (HAP), bloodstrea...

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Autores principales:	Martina Barchitta, Andrea Maugeri, Maria Clara La Rosa, Claudia La Mastra, Giuseppe Murolo, Giovanni Corrao, Antonella Agodi
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	DALYs hospital-acquired infections prevalence study pneumoniae bloodstream infection surgical site infection Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/a4e5343ec6d44bfea28c2063c09b5e3a
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spelling	oai:doaj.org-article:a4e5343ec6d44bfea28c2063c09b5e3a2021-11-25T16:23:36ZBurden of Healthcare-Associated Infections in Sicily, Italy: Estimates from the Regional Point Prevalence Surveys 2016–201810.3390/antibiotics101113602079-6382https://doaj.org/article/a4e5343ec6d44bfea28c2063c09b5e3a2021-11-01T00:00:00Zhttps://www.mdpi.com/2079-6382/10/11/1360https://doaj.org/toc/2079-6382An assessment of the burden of healthcare-associated infections (HAIs) in terms of disability-adjusted life years (DALYs) is useful for comparing and ranking HAIs and to support infection prevention and control strategies. We estimated the burden of healthcare-associated pneumoniae (HAP), bloodstream infection (HA BSI), urinary tract infection (HA UTI), and surgical site infection (SSI) in Sicily, Italy. We used data from 15,642 patients aged 45 years and above, identified during three repeated point prevalence surveys (PPSs) conducted from 2016 to 2018 according to the European Centre for Disease Prevention and Control protocol. The methodology of the Burden of Communicable Diseases in Europe project was employed. The selected HAIs accounted for 8424 DALYs (95% uncertainty interval (UI): 7394–9605) annually in Sicily, corresponding to 344 DALYs per 100,000 inhabitants aged 45 years and above (95% UI: 302–392). Notably, more than 60% of the burden was attributable to HAP, followed by HA BSI, SSI, and HA UTI. The latter had the lowest burden despite a relatively high incidence, whereas HA BSI generated a high burden even through a relatively low incidence. Differences between our estimates and those of European and Italian PPSs encourage the estimation of the burden of HAIs region by region.Martina BarchittaAndrea MaugeriMaria Clara La RosaClaudia La MastraGiuseppe MuroloGiovanni CorraoAntonella AgodiMDPI AGarticleDALYshospital-acquired infectionsprevalence studypneumoniaebloodstream infectionsurgical site infectionTherapeutics. PharmacologyRM1-950ENAntibiotics, Vol 10, Iss 1360, p 1360 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	DALYs hospital-acquired infections prevalence study pneumoniae bloodstream infection surgical site infection Therapeutics. Pharmacology RM1-950
spellingShingle	DALYs hospital-acquired infections prevalence study pneumoniae bloodstream infection surgical site infection Therapeutics. Pharmacology RM1-950 Martina Barchitta Andrea Maugeri Maria Clara La Rosa Claudia La Mastra Giuseppe Murolo Giovanni Corrao Antonella Agodi Burden of Healthcare-Associated Infections in Sicily, Italy: Estimates from the Regional Point Prevalence Surveys 2016–2018
description	An assessment of the burden of healthcare-associated infections (HAIs) in terms of disability-adjusted life years (DALYs) is useful for comparing and ranking HAIs and to support infection prevention and control strategies. We estimated the burden of healthcare-associated pneumoniae (HAP), bloodstream infection (HA BSI), urinary tract infection (HA UTI), and surgical site infection (SSI) in Sicily, Italy. We used data from 15,642 patients aged 45 years and above, identified during three repeated point prevalence surveys (PPSs) conducted from 2016 to 2018 according to the European Centre for Disease Prevention and Control protocol. The methodology of the Burden of Communicable Diseases in Europe project was employed. The selected HAIs accounted for 8424 DALYs (95% uncertainty interval (UI): 7394–9605) annually in Sicily, corresponding to 344 DALYs per 100,000 inhabitants aged 45 years and above (95% UI: 302–392). Notably, more than 60% of the burden was attributable to HAP, followed by HA BSI, SSI, and HA UTI. The latter had the lowest burden despite a relatively high incidence, whereas HA BSI generated a high burden even through a relatively low incidence. Differences between our estimates and those of European and Italian PPSs encourage the estimation of the burden of HAIs region by region.
format	article
author	Martina Barchitta Andrea Maugeri Maria Clara La Rosa Claudia La Mastra Giuseppe Murolo Giovanni Corrao Antonella Agodi
author_facet	Martina Barchitta Andrea Maugeri Maria Clara La Rosa Claudia La Mastra Giuseppe Murolo Giovanni Corrao Antonella Agodi
author_sort	Martina Barchitta
title	Burden of Healthcare-Associated Infections in Sicily, Italy: Estimates from the Regional Point Prevalence Surveys 2016–2018
title_short	Burden of Healthcare-Associated Infections in Sicily, Italy: Estimates from the Regional Point Prevalence Surveys 2016–2018
title_full	Burden of Healthcare-Associated Infections in Sicily, Italy: Estimates from the Regional Point Prevalence Surveys 2016–2018
title_fullStr	Burden of Healthcare-Associated Infections in Sicily, Italy: Estimates from the Regional Point Prevalence Surveys 2016–2018
title_full_unstemmed	Burden of Healthcare-Associated Infections in Sicily, Italy: Estimates from the Regional Point Prevalence Surveys 2016–2018
title_sort	burden of healthcare-associated infections in sicily, italy: estimates from the regional point prevalence surveys 2016–2018
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/a4e5343ec6d44bfea28c2063c09b5e3a
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Burden of Healthcare-Associated Infections in Sicily, Italy: Estimates from the Regional Point Prevalence Surveys 2016–2018

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