β-actin dependent chromatin remodeling mediates compartment level changes in 3D genome architecture
β-actin loss can affect gene expression and heterochromatin organization. Here the authors conduct a comprehensive genomic analysis of β-actin knockout mouse embryonic fibroblasts (MEFs) to investigate the impact of changes in β-actin levels on 3d genome architecture and chromatin remodeling activit...
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Autores principales: | Syed Raza Mahmood, Xin Xie, Nadine Hosny El Said, Tomas Venit, Kristin C. Gunsalus, Piergiorgio Percipalle |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/a4ea5e63186c4d90956c74c8cb8afbca |
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