Identification of Recessive Lethal Alleles in the Diploid Genome of a <named-content content-type="genus-species">Candida albicans</named-content> Laboratory Strain Unveils a Potential Role of Repetitive Sequences in Buffering Their Deleterious Impact
ABSTRACT The heterozygous diploid genome of Candida albicans is highly plastic, with frequent loss of heterozygosity (LOH) events. In the SC5314 laboratory strain, while LOH events are ubiquitous, a chromosome homozygosis bias is observed for certain chromosomes, whereby only one of the two homologs...
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| Main Authors: | , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2019
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| Subjects: | |
| Online Access: | https://doaj.org/article/a4f19e583b0040988497b79b9662e61f |
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