Intravitreal triamcinolone acetonide for rebound phenomenon after high-dose intravenous steroid treatment in Vogt-Koyanagi-Harada disease

Ik Soo Byon1, Ji Hun Kim1, Ji Eun Lee1,2, Boo Sup Oum1,2 1Department of Ophthalmology, Pusan National University Hospital; 2Medical Institute, School of Medicine, Pusan National University, Busan, Republic of Korea Abstract: The authors report two cases of rebound phenomenon treated with intravitrea...

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Autores principales:	Byon IS, Kim JH, Lee JE, Oum BS
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/a4f76c0134ba43c8a701b2a71892208e
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spelling	oai:doaj.org-article:a4f76c0134ba43c8a701b2a71892208e2021-12-02T04:31:28ZIntravitreal triamcinolone acetonide for rebound phenomenon after high-dose intravenous steroid treatment in Vogt-Koyanagi-Harada disease1177-54671177-5483https://doaj.org/article/a4f76c0134ba43c8a701b2a71892208e2011-11-01T00:00:00Zhttp://www.dovepress.com/intravitreal-triamcinolone-acetonide-for-rebound-phenomenon-after-high-a8602https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Ik Soo Byon1, Ji Hun Kim1, Ji Eun Lee1,2, Boo Sup Oum1,2 1Department of Ophthalmology, Pusan National University Hospital; 2Medical Institute, School of Medicine, Pusan National University, Busan, Republic of Korea Abstract: The authors report two cases of rebound phenomenon treated with intravitreal triamcinolone acetonide in Vogt-Koyanagi-Harada (VKH) disease. Patients in the acute phase of VKH disease were treated with high-dose intravenous (IV) methylprednisolone (1 g/day) for 3 days. Serous retinal detachment decreased and visual acuity improved during IV steroid treatment. After switching to oral steroid treatment, choroiditis and visual acuity worsened. An injection of triamcinolone acetonide (4 mg) into the vitreous resulted in gradual resolution of subretinal fluid and improvement of visual acuity. Systemic steroids were tapered to discontinuation without a relapse of inflammation. Adjuvant intravitreal triamcinolone is useful in the management of the rebound phenomenon in VKH disease. Keywords: adjuvant intravitreal steroid, serous retinal detachment, visual acuity, choroiditisByon ISKim JHLee JEOum BSDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 1589-1591 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Byon IS Kim JH Lee JE Oum BS Intravitreal triamcinolone acetonide for rebound phenomenon after high-dose intravenous steroid treatment in Vogt-Koyanagi-Harada disease
description	Ik Soo Byon1, Ji Hun Kim1, Ji Eun Lee1,2, Boo Sup Oum1,2 1Department of Ophthalmology, Pusan National University Hospital; 2Medical Institute, School of Medicine, Pusan National University, Busan, Republic of Korea Abstract: The authors report two cases of rebound phenomenon treated with intravitreal triamcinolone acetonide in Vogt-Koyanagi-Harada (VKH) disease. Patients in the acute phase of VKH disease were treated with high-dose intravenous (IV) methylprednisolone (1 g/day) for 3 days. Serous retinal detachment decreased and visual acuity improved during IV steroid treatment. After switching to oral steroid treatment, choroiditis and visual acuity worsened. An injection of triamcinolone acetonide (4 mg) into the vitreous resulted in gradual resolution of subretinal fluid and improvement of visual acuity. Systemic steroids were tapered to discontinuation without a relapse of inflammation. Adjuvant intravitreal triamcinolone is useful in the management of the rebound phenomenon in VKH disease. Keywords: adjuvant intravitreal steroid, serous retinal detachment, visual acuity, choroiditis
format	article
author	Byon IS Kim JH Lee JE Oum BS
author_facet	Byon IS Kim JH Lee JE Oum BS
author_sort	Byon IS
title	Intravitreal triamcinolone acetonide for rebound phenomenon after high-dose intravenous steroid treatment in Vogt-Koyanagi-Harada disease
title_short	Intravitreal triamcinolone acetonide for rebound phenomenon after high-dose intravenous steroid treatment in Vogt-Koyanagi-Harada disease
title_full	Intravitreal triamcinolone acetonide for rebound phenomenon after high-dose intravenous steroid treatment in Vogt-Koyanagi-Harada disease
title_fullStr	Intravitreal triamcinolone acetonide for rebound phenomenon after high-dose intravenous steroid treatment in Vogt-Koyanagi-Harada disease
title_full_unstemmed	Intravitreal triamcinolone acetonide for rebound phenomenon after high-dose intravenous steroid treatment in Vogt-Koyanagi-Harada disease
title_sort	intravitreal triamcinolone acetonide for rebound phenomenon after high-dose intravenous steroid treatment in vogt-koyanagi-harada disease
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/a4f76c0134ba43c8a701b2a71892208e
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Intravitreal triamcinolone acetonide for rebound phenomenon after high-dose intravenous steroid treatment in Vogt-Koyanagi-Harada disease

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